Cascarilla

Botanical Overview

Cascarilla (Croton eluteria) belongs to the Euphorbiaceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. The spurge family (Euphorbiaceae) includes an extremely diverse group of plants ranging from small herbs to large trees, many with milky sap that can be irritating or toxic. The flowers are typically small and unisexual, often arranged in distinctive inflorescences. Many species contain diterpene esters and other bioactive compounds.

General Description

It has been naturalized in other tropical regions of the Americas. It grows to be a small tree or tall shrub, rarely reaching 20 feet (6 m) in height. Its leaves are scanty, alternate, ovate-lanceolate, averaging 2 inches (5 cm) long, with close scaling below, giving a metallic silver-bronze appearance, and scattered white scales above. The flowers are small, with white petals, and very fragrant, appearing in March and April. The scented bark is fissured, pale yellowish brown, and may be covered in lichen.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Euphorbiaceae family is large and globally distributed. Notable medicinal members include:

Geographic Distribution

Cascarilla has been recorded in 10 countries and territories worldwide, including Australia, Bahamas, Cuba, Dominican Republic, Haiti, and others.

Traditional Uses

Cascarilla has been traditionally used for nervous system disorders and metabolic and nutritional health.

Nervous system disorders.

  • Narcotic

Nervous system support involves taking the herb as a warm tea, often in the evening or before bed. The calming compounds interact with neurotransmitter systems to promote relaxation and restful sleep.

Metabolic and nutritional health.

  • Tonic

Metabolic applications include consuming the plant as a food, fresh juice, or herbal infusion. Regular use supports the body’s natural metabolic processes and nutritional status.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Phenolic: antioxidant compounds that neutralize free radicals
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Australia, Bahamas, Cuba, Dominican Republic, Haiti, Jamaica, Cayman Islands, Netherlands, Turks and Caicos, United States.

Complete Use Records

CategoryCultural Context
TonicElsewhere, Turkey
BalsamicElsewhere
FumigantTurkey
NarcoticTurkey
DigestiveTurkey

Complete Chemical Inventory

CompoundFormulaMW
ALPHA-CALACORENEC₁₅H₂₀200.32 Da
ALPHA-COPAENEC₁₅H₂₄204.35 Da
ALPHA-PINENEC₁₀H₁₆136.23 Da
ALPHA-THUJENEC₁₀H₁₆136.23 Da
BETA-CARYOPHYLLENEC₁₅H₂₄204.35 Da
BETA-ELEMENEC₁₅H₂₄204.35 Da
BETA-PINENEC₁₀H₁₆136.23 Da
BETAINEC₅H₁₁NO₂117.15 Da
BORNEOLC₁₀H₁₈O154.25 Da
CALAMENENEC₁₅H₂₂202.33 Da
CAMPHENEC₁₀H₁₆136.23 Da
CASCARILLADIENEC₁₅H₂₄204.35 Da
CASCARILLIC-ACIDC₁₁H₂₀O₂184.27 Da
CASCARILLIDONE
CASCARILLIN-A
CASCARILLONEC₂₀H₃₀O₂302.5 Da
CINEOLEC₁₀H₁₈O154.25 Da
CUPARENEC₁₅H₂₂202.33 Da
CUPAROPHENOL
D-LIMONENEC₁₀H₁₆136.23 Da
DIPENTENEC₁₀H₁₆136.23 Da
EUGENOLC₁₀H₁₂O₂164.20 Da
EUPAROPHENOL
GAMMA-TERPINENEC₁₀H₁₆136.23 Da
GAMMA-TERPINEOLC₁₀H₁₈O154.25 Da
LIGNINC₁₈H₁₃N₃Na₂O₈S₂509.4 Da
LINALOLC₁₀H₁₈O154.25 Da
METHYL-THYMOLC₁₁H₁₆O164.24 Da
MYRCENEC₁₀H₁₆136.23 Da
P-CYMENEC₁₀H₁₄134.22 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources