Saffron

Botanical Overview

Saffron (Crocus sativus) is a flowering plant in the Iridaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. This species belongs to the Iridaceae family, a group of flowering plants.

General Description

A cormous autumn-flowering cultivated perennial, unknown in the wild, it is best known for the culinary use of its floral stigmas as the spice saffron. Human cultivation of saffron crocus and the trade and use of saffron have endured for more than 3,500 years and span different cultures, continents, and civilizations.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Iridaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Saffron has been recorded in 10 countries and territories worldwide, including Switzerland, Germany, Spain, France, Greece, and others.

Traditional Uses

Saffron has been traditionally used for digestive health, respiratory conditions, and pain and inflammation, among other applications.

Digestive health.

  • Carminative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Catarrh
  • Cold

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Pain and inflammation.

  • Anodyne

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic, Poison, Abortifacient. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Switzerland, Germany, Spain, France, Greece, India, Italy, United States, Uzbekistan, Unknown.

Complete Use Records

CategoryCultural Context
EmmenagogueElsewhere, Japan, Java, Turkey
SedativeElsewhere, Japan, Japan*
StimulantChina, Elsewhere, Turkey
AnodyneChina, Turkey
CardiotonicSpain, Turkey
CarminativeChina, Turkey
FeverElsewhere, Iraq
MeaslesElsewhere, Iraq
MelancholyElsewhere, Iraq
NarcoticElsewhere, Turkey
PoisonElsewhere, Turkey
SpasmChina, Elsewhere
AbortifacientElsewhere
AntispasmodicJapan*
AphrodisiacTurkey
BalsamicJapan
BloodChina
CancerEurope
CataplasmFrance
CatarrhElsewhere
ColdJapan
DiaphoreticElsewhere
FrightChina
GastrotonicJapan
HepatitisElsewhere
HepatomegalyIraq
HysteriaElsewhere
MegalosplenyElsewhere
MenoxeniaChina
NervineTurkey

Complete Chemical Inventory

CompoundFormulaMW
1,8-CINEOLEC₁₀H₁₈O154.25 Da
13-CIS-CROCINC₄₄H₆₄O₂₄977.0 Da
2-BUTENOIC-ACID-LACTONE
2-HYDROXY-3,5,5-TRIMETHYLCYCLOHEXA-1,4-DION-2-ENE
2-PHENETHANOLC₈H₁₀O122.16 Da
2-PHENYLETHANOLC₈H₁₀O122.16 Da
3,5,5-TRIMETHYL-4-HYDROXY-1-CYCLOHEXANONE-2-ENEC₉H₁₄O₂154.21 Da
3,5,5-TRIMETHYLCYCLOHEXA-1,4-DION-2-ENE
3,5,5-TRIMETHYLCYCLOHEXA-1,4-DIONE
3,8-DIHYDROXY-1-METHYLANTHRAQUINONE-2-CARBOXYLIC-ACID
4-HYDROXY-2,6,6-TRIMETHYL-CYCLOHEX-1-ENE-CARBOXALDEHYDE
4-HYDROXY-3,5,5-TRIMETHYLCYCLOHEXAN-1-ON-2-ENE
6-HYDROXY-3-FORMYL-2,4,4-TRIMETHYLCYCLOHEXA-2,5-DIEN-1-ONE
ALANINEC₃H₇NO₂89.09 Da
ALPHA-CROCETINC₂₀H₂₄O₄328.4 Da
ALPHA-CROCINC₄₄H₆₄O₂₄977.0 Da
ALPHA-PINENEC₁₀H₁₆136.23 Da
ALPHA-TERPINENEC₁₀H₁₆136.23 Da
ALPHA-THUJENEC₁₀H₁₆136.23 Da
ARGININEC₆H₁₄N₄O₂174.20 Da
ASH
ASPARTIC-ACIDC₄H₇NO₄133.10 Da
ASTRAGALINC₂₁H₂₀O₁₁448.4 Da
BETA-CAROTENEC₄₀H₅₆536.9 Da
BETA-CITRONELLOLC₁₀H₂₀O156.26 Da
BETA-CROCETINC₂₁H₂₆O₄342.4 Da
BETA-MYRCENEC₁₀H₁₆136.23 Da
BETA-PHENYLETHANOLC₈H₁₀O122.16 Da
BETA-PINENEC₁₀H₁₆136.23 Da
BORNEOLC₁₀H₁₈O154.25 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources