Guggul

Also known as: Indian Bdellium-Tree

Botanical Overview

Guggul (Commiphora wightii) is a species in the Burseraceae family. This species belongs to the Burseraceae family, a group of flowering plants. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

General Description

The species is native to western India, from where it was introduced westward to southern Pakistan and the middle-east. It prefers arid and semi-arid climates and is tolerant of poor soil.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Burseraceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Guggul has been recorded in 7 countries and territories worldwide, including India, Oman, Pakistan, Sweden, United States, and others.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. The limited documentation available for this species represents an opportunity for ethnobotanical research.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: India, Oman, Pakistan, Sweden, United States, Yemen, Unknown.

Complete Chemical Inventory

CompoundFormulaMW
(+)-SESAMINC₂₀H₁₈O₆354.4 Da
10-BETA-HYDROXY-PREGN-4-EN-3-ONE
16-ALPHA-HYDROXY-PREGN-4-EN-3-ONE
20(R)-HYDROXY-PREGN-4-EN-3-ONE
20(S)-HYDROXY-PREGN-4-EN-3-ONE
20-ALPHA-HYDROXY-PREGN-4-EN-3-ONEC₂₁H₃₂O₂316.5 Da
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-DOCOSANE-1-2-3-4-TETRAOL-1-YL-ESTER
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-EICOSANE-1-2-3-4-TETRAOL-1-YL-ESTER
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-HENEICOSANE-1-2-3-4-TETRAOL-1-YL-ESTER
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-HEPTADECANE-1-2-3-4-TETRAOL-1-YL-ESTER
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-HEXADECANE-1-2-3-4-TETRAOL-1-YL-ESTER
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-NONADECANE-1-2-3-4-TETRAOL-1-YL-ESTER
3-(4-HYDROXY-3-METHOXY-PHENYL)-PROPANOIC-ACID-OCTADECANE-1-2-3-4-TETRAOL-1-YL-ESTER
ALLO-CEMBROL
ALLYL-CEMBROL
ALUMINUMAl26.981538 Da
AMINO-ACIDS
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CALCIUMCa40.08 Da
CEMBRENE-AC₂₀H₃₂272.5 Da
CHOLESTEROLC₂₇H₄₆O386.7 Da
CIS-GUGGULSTEROL
CIS-GUGGULSTERONEC₂₁H₂₈O₂312.4 Da
COMMIPHORA-MUKUL-KETO-STEROID
COMMIPHORA-MUKUL-STEROID
COMMIPHORA-MUKUL-STEROL
COPPERCu63.55 Da
EICOSANE-1-2-3-4-TETROL
ELLAGIC-ACIDC₁₄H₆O₈302.19 Da
FERULIC-ACIDC₁₀H₁₀O₄194.18 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources