Stone Root

Botanical Overview

Stone Root (Collinsonia canadensis) is a flowering plant in the Lamiaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide.

General Description

It is native to eastern North America, primarily east of the Mississippi River, where it is widespread. It is the most broadly distributed member of the genus Collinsonia, ranging north to Quebec and south to Florida. Its natural habitat is nutrient-rich mesic forests, most often in rocky, calcareous areas. Collinsonia canadensis can grow up to 4 feet (1. 2 m) tall and has terminal clusters of tiny, tubular yellow flowers. Leaves are green, large, sharply toothed, and ovate. It produces lemon-scented flowers in mid-summer, a time when little else is in bloom in densely shaded forests.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Stone Root has been recorded in 10 countries and territories worldwide, including Belgium, Canada, Switzerland, Germany, United Kingdom, and others.

Traditional Uses

Stone Root has been traditionally used for digestive health, skin and wound care, and urinary tract health, among other applications.

Digestive health.

  • Colic
  • Stomachic
  • Dyspepsia

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Wound

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 18 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Tannin: astringent compounds that tighten tissues and resist infection
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Belgium, Canada, Switzerland, Germany, United Kingdom, Italy, Netherlands, Norway, United States, Unknown.

Complete Use Records

CategoryCultural Context
DiureticElsewhere, Turkey
DropsyElsewhere, US
SpasmTurkey, US(Appalachia)
Ache(Head)US(Appalachia)
ColicElsewhere
DiaphoreticElsewhere
PilesUS
SedativeTurkey
StomachicTurkey
WoundUS(Appalachia)
MedicineUS(Appalachia)
AstringentTurkey
DyspepsiaUS(Appalachia)
RespiratoryUS
SudorificTurkey
TonicTurkey

Complete Chemical Inventory

CompoundFormulaMW
16-ALPHA-HYDROXYHEDERAGENIN
AKEBOSIDE
ALPHA-NAGITANINE
ALPHA-PINENEC₁₀H₁₆136.23 Da
BETA-ELEMENEC₁₅H₂₄204.35 Da
BETA-PINENEC₁₀H₁₆136.23 Da
CARYOPHYLLENEC₁₅H₂₄204.35 Da
COLLINSOGENIN
COLLINSONIDINC₄₁H₆₆O₁₃767.0 Da
COLLINSONINC₃₅H₅₆O₉620.8 Da
DELTA-CADINENEC₁₅H₂₄204.35 Da
ELEMICINC₁₂H₁₆O₃208.25 Da
GERMACRENE-DC₁₅H₂₄204.35 Da
HEDERAGENIN-3-O-ALPHA-ARABINOPYRANOSIDE
LIMONENEC₁₀H₁₆136.23 Da
MUCILAGE
ROSMARINIC-ACIDC₁₈H₁₆O₈360.3 Da
TANNIN

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources