Forskohl's Coleus

Botanical Overview

Forskohl’s Coleus (Coleus forskohlii) is a species in the Lamiaceae family. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 20 compounds in this species, suggesting potential medicinal value.

General Description

It is known by the common name woolly plectranthus. It produces forskolin, an extract useful for pharmaceutical preparations and research in cell biology.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Forskohl’s Coleus has been recorded in 10 countries and territories worldwide, including Brazil, Bhutan, China, Guatemala, India, and others.

Active Compounds

Phytochemical research has identified 20 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Further ethnobotanical and pharmacological research may reveal additional therapeutic applications for this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Brazil, Bhutan, China, Guatemala, India, Kenya, Sri Lanka, Nepal, Uganda, Venezuela.

Complete Chemical Inventory

CompoundFormulaMW
(+)-FERRUGINOLC₂₀H₃₀O286.5 Da
1,9-DIDEOXY-7-DEACETYL-FORSKOHLIN
1,9-DIDEOXYFORSKOHLIN
20-DEOXOCARNOSOLC₂₀H₂₈O₃316.4 Da
3BETA-HYDROXY-3-DEOXYBARBATUSIN
6BETA,7BETA,9ALPHA-TRIHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
6BETA-HYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
6BETA-HYDROXY-CARNOSOL
7BETA-ACETOXY-6BETA,9ALPHA-DIHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE
8,13-EPOXY-LABD-14-EN-11-ONE
9-DEOXYFORSKOHLIN
BARBATUSIN
BARBATUSOLC₂₀H₂₈O₂300.4 Da
COLEOL
COLEONOLS
COLEONS
COLEOSOL
CYCLOBUTATUSIN
DEACETYL-FORSKOHLIN
FORSKOLINC₂₂H₃₄O₇410.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources