Botanical Overview
Commonly known as Butua, this species belongs to the Menispermaceae family. Traditional healers across continents have independently recognized the medicinal value of this species, leading to one of the most extensive ethnobotanical records available. This species belongs to the Menispermaceae family, a group of flowering plants.

General Description
Cissampelos pareira (velvetleaf) is a species of flowering plant in the family Menispermaceae.
Family Context
The Menispermaceae family is widely distributed. Notable medicinal members include:
- Moonseed — 16 documented uses
- Indian Tape-Vine — 12 documented uses
- Levant Berry — 9 documented uses
- Calumba Root — 9 documented uses
Geographic Distribution
Butua has been recorded in 10 countries and territories worldwide, including Argentina, Brazil, Colombia, Costa Rica, India, and others.
Traditional Uses
Butua has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.
Digestive health.
- Diarrhea
- Colic
- Dysentery
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Respiratory conditions.
- Expectorant
- Asthma
- Bronchitis
- Cold
- Cough
Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.
Skin and wound care.
- Boil
- Wound
For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.
Active Compounds
Phytochemical research has identified 21 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Alkaloid: nitrogenous compounds with diverse pharmacological activities
- Saponin: soap-like compounds with immune-modulating activity