Butua

Also known as: False Pareira, Pareira

Botanical Overview

Commonly known as Butua, this species belongs to the Menispermaceae family. Traditional healers across continents have independently recognized the medicinal value of this species, leading to one of the most extensive ethnobotanical records available. This species belongs to the Menispermaceae family, a group of flowering plants.

General Description

Cissampelos pareira (velvetleaf) is a species of flowering plant in the family Menispermaceae.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Menispermaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Butua has been recorded in 10 countries and territories worldwide, including Argentina, Brazil, Colombia, Costa Rica, India, and others.

Traditional Uses

Butua has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Diarrhea
  • Colic
  • Dysentery

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Expectorant
  • Asthma
  • Bronchitis
  • Cold
  • Cough

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Boil
  • Wound

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 21 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Saponin: soap-like compounds with immune-modulating activity
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Argentina, Brazil, Colombia, Costa Rica, India, Madagascar, Mexico, Nicaragua, Nepal, Paraguay.

Complete Use Records

CategoryCultural Context
Bite(Snake)Elsewhere, Guatemala, Haiti, Mexico, Mexico(Chinantec), Panama(Choco), Venezuela
FeverElsewhere, Guatemala, Mexico, Mexico(Chinantec)
DiureticElsewhere, Mexico, Venezuela
BladderMexico, Venezuela
BoilIndia, Trinidad
DiarrheaElsewhere, India(Santal)
DropsyElsewhere, Mexico
EmmenagogueElsewhere, Mexico
ExpectorantElsewhere, Mexico
HypertensionElsewhere, Trinidad
PiscicideElsewhere, Malaya
TonicIndia, Mexico
UrogenitalElsewhere, Mexico
WoundIndia, India(Bhil)
AnecbolicElsewhere
AntidoteGuatemala
AntiecbolicElsewhere
AsthmaElsewhere
Bite(Dog)India(Santal)
BronchitisIndia(Santal)
ChillIndia(Santal)
ColdIndia(Santal)
ColicIndia(Santal)
CoughElsewhere
CystitisElsewhere
DeliriumIndia(Santal)
DysenteryIndia(Santal)
ErysipelasGuatemala
FebrifugeElsewhere
HematuriaIndia(Santal)

Complete Chemical Inventory

CompoundFormulaMW
(+)-CURINEC₃₆H₃₈N₂O₆594.7 Da
(++)-CURINE-4'-METHYL-ETHER
4'-O-METHYLCURINE
ALKALOIDS
BEBEERINEC₃₆H₃₈N₂O₆594.7 Da
CISSAMINEC₂₀H₂₄NO₄+342.4 Da
CISSAMPAREINEC₃₇H₃₈N₂O₆606.7 Da
CYCLANOLINEC₂₀H₂₄NO₄+342.4 Da
CYCLEANINEC₃₈H₄₂N₂O₆622.7 Da
D-QUERCITOLC₆H₁₂O₅164.16 Da
HAYATIDINE
HAYATINEC₃₆H₃₈N₂O₆594.7 Da
HAYATININEC₃₇H₄₀N₂O₆608.7 Da
ISOCHONDODENDRINEC₃₆H₃₈N₂O₆594.7 Da
MENISMINE
PARIERINE
PELOSINEC₃₆H₃₈N₂O₆594.7 Da
QUERCITOLC₆H₁₂O₅164.16 Da
SAPONINC₅₈H₉₄O₂₇1223.3 Da
TETRANDRINEC₃₈H₄₂N₂O₆622.7 Da
TETRANDRINE-N-2'-OXIDE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources