Lojabark

Also known as: Quinine

Botanical Overview

Lojabark (Cinchona officinalis) is a flowering plant in the Rubiaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The coffee family (Rubiaceae) includes trees, shrubs, and herbs with opposite leaves and interpetiolar stipules. The flowers are typically tubular with four or five petals. The family includes coffee (Coffea), quinine-producing Cinchona, and numerous other medicinal species with alkaloid constituents.

General Description

It is native to wet montane forests in Colombia, Ecuador, Peru and Bolivia, between 1600–2700 meters above sea level. It is the national tree of Peru.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Rubiaceae family is large and primarily tropical. Notable medicinal members include:

Geographic Distribution

Lojabark has been recorded in 10 countries and territories worldwide, including Bolivia, Brazil, China, Colombia, Ecuador, and others.

Traditional Uses

Lojabark has been traditionally used for digestive health, respiratory conditions, and pain and inflammation, among other applications.

Digestive health.

  • Stomachic
  • Dysentery

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Cold
  • Pneumonia

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Pain and inflammation.

  • Neuralgia
  • Lumbago

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 9 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
  • Tannin: astringent compounds that tighten tissues and resist infection
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Bolivia, Brazil, China, Colombia, Ecuador, Indonesia, India, Jamaica, Peru, Unknown.

Complete Use Records

CategoryCultural Context
TonicElsewhere, Mexico, Turkey
AntisepticMexico, Turkey
AstringentMexico, Turkey
MalariaElsewhere, Mexico
AmebiasisElsewhere
BactericideElsewhere
ColdElsewhere
ContraceptiveElsewhere
FeverTurkey
FluElsewhere
HangoverChina
NeuralgiaElsewhere
PertussisElsewhere
PilesElsewhere
PinwormsElsewhere
PneumoniaElsewhere
SchizonticideElsewhere
SciaticaElsewhere
SepticemiaElsewhere
StomachicElsewhere
TyphoidElsewhere
VaricosityElsewhere
UterotonicElsewhere
AnestheticElsewhere
CarditisElsewhere
DysenteryElsewhere
InsecticideElsewhere
LumbagoElsewhere
NalariaTurkey
NeuritisElsewhere

Complete Chemical Inventory

CompoundFormulaMW
3-ALPHA,17-BETA-CINCHOPHYLLINEC₃₁H₃₆N₄O₂496.6 Da
3-BETA,17-BETA-CINCHOPHYLLINEC₃₁H₃₆N₄O₂496.6 Da
AVICULARINC₂₀H₁₈O₁₁434.3 Da
CINCHONIDINEC₁₉H₂₂N₂O294.4 Da
CINCHONINEC₁₉H₂₂N₂O294.4 Da
HYDROQUINIDINEC₂₀H₂₆N₂O₂326.4 Da
QUINIDINEC₂₀H₂₄N₂O₂324.4 Da
QUININEC₂₀H₂₄N₂O₂324.4 Da
TANNIN

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources