Curare

Botanical Overview

Curare (Chondrodendron tomentosum) belongs to the Menispermaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. This species belongs to the Menispermaceae family, a group of flowering plants.

General Description

It is a large tropical liana native to Central and South America. It contains highly toxic alkaloids and is one of the sources of the arrow poison curare – specifically ’tube curare’, the name of which is derived from the name of the medicinally valuable alkaloid tubocurarine.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Menispermaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Curare has been recorded in 9 countries and territories worldwide, including Bolivia, Brazil, Colombia, Ecuador, Jamaica, and others.

Traditional Uses

Curare has been traditionally used for urinary tract health, fever management, and metabolic and nutritional health, among other applications.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Metabolic and nutritional health.

  • Tonic

Metabolic applications include consuming the plant as a food, fresh juice, or herbal infusion. Regular use supports the body’s natural metabolic processes and nutritional status.

Active Compounds

Phytochemical research has identified 14 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Poison. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Bolivia, Brazil, Colombia, Ecuador, Jamaica, Panama, Peru, Paraguay, United States.

Complete Use Records

CategoryCultural Context
Poison(Arrow)Brazil, Peru, Venezuela
DiureticElsewhere, German
TonicElsewhere, German
PoisonSouth America, US
AperientGerman
FeverSpanish
AntisepticFrench

Complete Chemical Inventory

CompoundFormulaMW
CHONDOCURARINE
CHONDOCURINEC₃₆H₃₈N₂O₆594.7 Da
CHONDODINE
CURINEC₃₆H₃₈N₂O₆594.7 Da
CYCLEANINEC₃₈H₄₂N₂O₆622.7 Da
D-TUBOCURARINEC₃₇H₄₁N₂O₆+609.7 Da
ISOCHONDODENDRINEC₃₆H₃₈N₂O₆594.7 Da
L-BEEBERINE
L-TUBOCURARINE
N-BENZYL-PHTHALIMIDE
NORCYCLEANINE
PELONINE
TOMENTOCURINE
TUBOCURARINEC₃₇H₄₁N₂O₆+609.7 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources