King's Cure

Also known as: Pipsissewa

Botanical Overview

King’s Cure (Chimaphila umbellata) is a flowering plant in the Ericaceae family. Traditional medicine systems have documented several valuable applications for this species, supported by its observed therapeutic effects. The heath family (Ericaceae) includes shrubs and small trees with simple, often evergreen leaves that are typically thick and leathery. The flowers are urn-shaped or bell-shaped with fused petals. Many species grow in acidic soils and form mycorrhizal associations, and several produce berries used in traditional medicine.

General Description

It is native throughout the cool temperate Northern Hemisphere.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Ericaceae family is widely distributed worldwide. Notable medicinal members include:

Geographic Distribution

King’s Cure has been recorded in 10 countries and territories worldwide, including Canada, Germany, Estonia, Finland, France, and others.

Traditional Uses

King’s Cure has been traditionally used for urinary tract health, pain and inflammation, and fever management, among other applications.

Urinary tract health.

  • Diuretic
  • Kidney

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Pain and inflammation.

  • Rheumatism

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Fever management.

  • Fever

Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.

Active Compounds

Phytochemical research has identified 27 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Canada, Germany, Estonia, Finland, France, Mexico, Poland, Russia, Sweden, United States.

Complete Use Records

CategoryCultural Context
FumitoryUS(Blackfoot), US(Flathead), US(Paiute)
DiureticDanish, US
AlterativeFrench
AntisepticUS
ApertifGerman
CancerUS(PA)
KidneyUS
LinimentCanada(Salish)
MedicineUS(Appalachia)
MyalgiaCanada(Salish)
RheumatismUS
StiffnessCanada(Salish)
StoneUS(Amerindian)
TeaUS
TonicUS
TyphusUS(Amerindian)
VulneraryUS
FeverUS(Blackfoot)
CollyriumUS(Flathead)
DiabetesUS
DigestiveFrench
StomachUS
SudorificUS(Amerindian)
AstringentGerman

Complete Chemical Inventory

CompoundFormulaMW
(-)-EPICATECHIN-GALLATEC₂₂H₁₈O₁₀442.4 Da
2,7-DIMETHYL-1,4-NAPTHOQUINONE
ARBUTINC₁₂H₁₆O₇272.25 Da
AVICULARINC₂₀H₁₈O₁₁434.3 Da
BETA-AMYRINC₃₀H₅₀O426.7 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CHIMAPHILINC₁₂H₁₀O₂186.21 Da
EPICATECHIN-GALLATEC₂₂H₁₈O₁₀442.4 Da
GUM
HENTRIACONTANEC₃₁H₆₄436.8 Da
HOMOGENTISIC-ACID-GLUCOSIDE
HYPEROSIDEC₂₁H₂₀O₁₂464.4 Da
ISOHOMOARBUTINC₁₃H₁₈O₇286.28 Da
KAEMPFEROLC₁₅H₁₀O₆286.24 Da
METHYL-SALICYLATEC₈H₈O₃152.15 Da
NONACOSANEC₂₉H₆₀408.8 Da
OLEANOLIC-ACIDC₃₀H₄₈O₃456.7 Da
RENIFOLINC₂₃H₃₄O₈438.5 Da
RESINC₁₅H₂₄204.35 Da
SALICYLIC-ACID-METHYL-ESTERC₈H₈O₃152.15 Da
STARCH
SUGARC₁₂H₂₂O₁₁342.30 Da
TANNIN
TARAXASTEROLC₃₀H₅₀O426.7 Da
TARAXEROLC₃₀H₅₀O426.7 Da
TOLUQUINOLC₇H₈O₂124.14 Da
URSOLIC-ACIDC₃₀H₄₈O₃456.7 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources