Epazote

Also known as: Wormseed

Botanical Overview

Epazote (Chenopodium ambrosioides) is a flowering plant in the Chenopodiaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. This species belongs to the Chenopodiaceae family, a group of flowering plants.

General Description

Dysphania ambrosioides, formerly Chenopodium ambrosioides, known as epazote, Jesuit’s tea, Mexican tea or wormseed, is an annual or short-lived perennial herb native to the Americas.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Chenopodiaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Epazote has been recorded in 10 countries and territories worldwide, including Brazil, Colombia, Spain, France, Japan, and others.

Traditional Uses

Epazote has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Vermifuge
  • Stomachic
  • Colic
  • Dysentery
  • Ache(Stomach)
  • Carminative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Asthma

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Sore

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Narcotic. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Brazil, Colombia, Spain, France, Japan, Mexico, Portugal, Paraguay, Taiwan, United States.

Complete Use Records

CategoryCultural Context
VermifugeBahamas, China, Dominican Republic, Elsewhere, Guatemala, Haiti, Mexico, Mexico(Chinantec), Panama, Spain, Trinidad, Turkey, US, Venezuela
AsthmaDominican Republic, Elsewhere, Panama, Trinidad, Turkey
StomachicBrazil, China, Turkey, Venezuela
EmmenagogueMexico, Turkey, US
StimulantElsewhere, Trinidad, Turkey
AmebiasisElsewhere, Trinidad
ColicDominican Republic, Mexico
DysenteryPanama, Trinidad
FungicideElsewhere, Trinidad
NervesMexico, US
PuerperiumTrinidad, US
SoreHaiti, Trinidad
TumorMexico, Peru
Ache(Stomach)Haiti
AnalgesicChina
AnemiaColombia
AnodyneUS
AntisepticHaiti
AscaricideElsewhere
CarminativeChina
ConjunctivitisDominican Republic
DiaphoreticMexico
DyspneaTrinidad
FatigueTrinidad
FearMexico
HookwormsElsewhere
LactogogueUS
NarcoticUS
NervineTurkey
PalpitationTrinidad

Complete Chemical Inventory

CompoundFormulaMW
ALPHA-PINENEC₁₀H₁₆136.23 Da
ARITASONE
ASCARIDOLEC₁₀H₁₆O₂168.23 Da
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
BETA-CAROTENEC₄₀H₅₆536.9 Da
BUTYRIC-ACIDC₄H₈O₂88.11 Da
CALCIUMCa40.08 Da
CARBOHYDRATES
D-CAMPHORC₁₀H₁₆O152.23 Da
FATC₁₆H₃₂O₂256.42 Da
FERULIC-ACIDC₁₀H₁₀O₄194.18 Da
FIBER
GERANIOLC₁₀H₁₈O154.25 Da
IRONFe55.84 Da
KILOCALORIES
L-PINOCARVONEC₁₀H₁₄O150.22 Da
LEUCINEC₆H₁₃NO₂131.17 Da
LIMONENEC₁₀H₁₆136.23 Da
MALIC-ACIDC₄H₆O₅134.09 Da
MENTHADIENEC₁₀H₁₆136.23 Da
METHYL-SALICYLATEC₈H₈O₃152.15 Da
MYRCENEC₁₀H₁₆136.23 Da
NIACINC₆H₅NO₂123.11 Da
P-CYMENEC₁₀H₁₄134.22 Da
P-CYMOLC₁₀H₁₄134.22 Da
PHOSPHORUSP30.97376200 Da
PROTEIN
RIBOFLAVINC₁₇H₂₀N₄O₆376.4 Da
SAFROLEC₁₀H₁₀O₂162.18 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources