Celandine

Botanical Overview

Celandine (Chelidonium majus) is a flowering plant in the Papaveraceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The poppy family (Papaveraceae) includes herbs with milky or colored sap and showy flowers with two or three sepals that fall off as the flower opens. The fruits are capsules with many small seeds. This family produces benzylisoquinoline alkaloids including morphine, codeine, and sanguinarine.

General Description

One of two species in the genus Chelidonium, it is native to Europe and western Asia and introduced widely in North America. The plant known as lesser celandine (Ficaria verna) is not closely related, as it belongs to the buttercup family Ranunculaceae.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Papaveraceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Celandine has been recorded in 10 countries and territories worldwide, including Austria, Belgium, Czech Republic, Germany, France, and others.

Traditional Uses

Celandine has been traditionally used for digestive health, respiratory conditions, and skin and wound care, among other applications.

Digestive health.

  • Vermifuge
  • Purgative
  • Laxative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Expectorant

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Skin and wound care.

  • Skin

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Poison, Narcotic, Purgative. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Austria, Belgium, Czech Republic, Germany, France, United Kingdom, Netherlands, Russia, Sweden, United States.

Complete Use Records

CategoryCultural Context
WartEstonia, Finland, Germany, Japan(Ainu), Lithuania, Morocco, Norway, Spain(Balearic I), UK, West Germany(Badan)
CancerAustria, US(Amerindian), USSR
AnodyneElsewhere, Turkey
CornGuatemala, Uruguay
DiureticElsewhere, Turkey
PoisonTurkey, US
SedativeElsewhere, Turkey
AlterativeTurkey
AntispasmodicElsewhere
Cancer(Stomach)Japan
CholagogueTurkey
DepurativeTurkey
DiaphoreticElsewhere
JaundiceSpain
NarcoticTurkey
SkinElsewhere
SpasmTurkey
VermifugeTurkey
AnalgesicChina
FatalityEurope
PurgativeElsewhere
FreckleElsewhere
LaxativeTurkey
ExpectorantElsewhere

Complete Chemical Inventory

CompoundFormulaMW
ALKALOIDS
ALLOCRYPTOPINEC₂₁H₂₃NO₅369.4 Da
ALPHA-HOMOCHELIDONINEC₂₁H₂₃NO₅369.4 Da
BERBERINEC₂₀H₁₈NO₄+336.4 Da
CHELAMIDINE
CHELAMINEC₂₀H₁₉NO₆369.4 Da
CHELERITINE
CHELERYTHRINEC₂₁H₁₈NO₄+348.4 Da
CHELIDAMINE
CHELIDONIC-ACIDC₇H₄O₆184.10 Da
CHELIDONINEC₂₀H₁₉NO₅353.4 Da
CHELIDONIOL
CHELILUTINEC₂₂H₂₀NO₅+378.4 Da
CHELIRUBINEC₂₁H₁₆NO₅+362.4 Da
CHOLINEC₅H₁₄NO+104.17 Da
CITRIC-ACIDC₆H₈O₇192.12 Da
COPTISINEC₁₉H₁₄NO₄+320.3 Da
CORYSAMINEC₂₀H₁₆NO₄+334.3 Da
DIHYDROSANGUINARINEC₂₀H₁₅NO₄333.3 Da
ERGOSTEROLC₂₈H₄₄O396.6 Da
FATC₁₆H₃₂O₂256.42 Da
FORMIC-ACIDCH₂O₂46.025 Da
GAMMA-HOMOCHELIDONINEC₂₁H₂₃NO₅369.4 Da
HISTAMINEC₅H₉N₃111.15 Da
HYDROXYCHELIDONINE
HYDROXYSANGUINARINEC₂₀H₁₃NO₅347.3 Da
L-SPARTEINEC₁₅H₂₆N₂234.38 Da
MAGNOFLORINEC₂₀H₂₄NO₄+342.4 Da
MALIC-ACIDC₄H₆O₅134.09 Da
METHOXYCHELIDONINEC₂₁H₁₇NO₆379.4 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources