Botanical Overview
Lanceleaf Periwinkle (Catharanthus lanceus) is a species in the Apocynaceae family. The dogbane family (Apocynaceae) includes herbs, shrubs, vines, and trees with milky sap containing alkaloids and cardiac glycosides. The flowers are typically five-petaled and often showy with a tubular corolla. Many species in this family are highly toxic but also source of important cardiac medications. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 25 compounds in this species, suggesting potential medicinal value.
General Description
Its fragrant flowers feature white or cream corolla lobes turning pink, reddish-violet or pink-magenta. Its habitat is on volcanic or burned soil, hillside rocks and in open woodland on ridges. Catharanthus lanceus is found from 750–2,000 metres (2,500–6,600 ft) altitude. The plant is used in local medicinal treatments for toothache, fever and skin diseases, and also as a diuretic. The species is endemic to Madagascar. Two alkaloids have been isolated from the root: lanceine and vinosidine.
Family Context
The Apocynaceae family is primarily tropical and subtropical. Notable medicinal members include:
- Alstonia scholaris — 42 documented uses
- Madagascar Periwinkle — 40 documented uses
- Oleander — 30 documented uses
- African Snakeroot — 28 documented uses
Geographic Distribution
Lanceleaf Periwinkle has been recorded in Madagascar, and United States.
Active Compounds
Phytochemical research has identified 25 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Alkaloid: nitrogenous compounds with diverse pharmacological activities
Research Status
Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.