Matasano

Also known as: White sapote

Botanical Overview

Matasano (Casimiroa edulis) is a flowering plant in the Rutaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The citrus family (Rutaceae) includes trees and shrubs with gland-dotted leaves that release aromatic oils when crushed. The flowers are typically white with four or five petals, and the fruits are often modified berries with a leathery rind. Most species produce alkaloids and limonoids with medicinal activity.

General Description

The genus is named for “an Otomi Indian, Casimiro Gómez, from the town of Cardonal in Hidalgo, Mexico, who fought and died in Mexico’s war of independence. “.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Rutaceae family is primarily tropical and subtropical. Notable medicinal members include:

Geographic Distribution

Matasano has been recorded in 10 countries and territories worldwide, including Brazil, Colombia, Costa Rica, Dominican Republic, Guatemala, and others.

Traditional Uses

Matasano has been traditionally used for digestive health, skin and wound care, and pain and inflammation, among other applications.

Digestive health.

  • Diarrhea
  • Vermifuge

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Ulcer
  • Sore

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Pain and inflammation.

  • Rheumatism

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Poison. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Brazil, Colombia, Costa Rica, Dominican Republic, Guatemala, Mexico, New Zealand, El Salvador, United States, South Africa.

Complete Use Records

CategoryCultural Context
DiarrheaElsewhere, Mexico
HypnoticElsewhere, Mexico
UlcerElsewhere, Mexico
AnalgesicMexico
CancerMexico
FeverMexico
NervineLatin America
RheumatismMexico
SedativeMexico
SoporificUS
VermifugeElsewhere
ConvulsionMexico
SoreMexico
SuppurativeMexico
VulneraryGerman
PoisonMexico

Complete Chemical Inventory

CompoundFormulaMW
5,6-DIMETHOXYFLAVONEC₁₇H₁₄O₄282.29 Da
7-ALPHA-OBACUNOLC₂₆H₃₂O₇456.5 Da
9-HYDROXY-4-METHOXY-FURANO-(3,2-G)-BENZOPYRAN-7-ON
ALPHA-FAGARINEC₂₁H₂₃NO₅369.4 Da
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
BERGAPTENC₁₂H₈O₄216.19 Da
BETA-CAROTENEC₄₀H₅₆536.9 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
BETA-SITOSTEROL-BETA-D-GLUCOSIDEC₃₅H₆₀O₆576.8 Da
CALCIUMCa40.08 Da
CARBOHYDRATES
CASIMIRLIDE
CASIMIROEDINEC₂₁H₂₇N₃O₆417.5 Da
CASIMIROINC₁₂H₁₁NO₄233.22 Da
CASIMIROINEC₁₂H₁₁NO₄233.22 Da
DEACETYL-NOMILIN
DICTAMNINEC₁₂H₉NO₂199.20 Da
EDULEIN
EDULININEC₁₆H₂₁NO₄291.34 Da
EDULITINC₁₁H₁₁NO₃205.21 Da
FATC₁₆H₃₂O₂256.42 Da
FIBER
IPURANOL
IRONFe55.84 Da
ISOPIMPINELLINC₁₃H₁₀O₅246.21 Da
KILOCALORIES
KOKUSAGININEC₁₄H₁₃NO₄259.26 Da
N-ALPHA,N-ALPHA-DIMETHYLHISTAMINEC₇H₁₃N₃139.20 Da
N-BENZOYLTYRAMINEC₁₅H₁₅NO₂241.28 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources