Safflower

Botanical Overview

Safflower (Carthamus tinctorius) is a flowering plant in the Asteraceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The daisy family (Asteraceae) is one of the largest plant families, characterized by composite flower heads (capitula) that contain many small florets surrounded by bracts. Plants range from tiny alpine herbs to large tropical trees. The family includes many medicinally important species with bitter compounds and essential oils.

General Description

It is one of the world’s oldest crops; today, it is commercially cultivated for vegetable oil extracted from the seeds. Plants are 30 to 150 cm tall with globular flower heads having yellow, orange, or red flowers. Each branch will usually have from one to five flower heads containing 15 to 20 seeds per head. Safflower is native to arid environments having seasonal rain. It grows a deep taproot which enables it to thrive in such environments.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Asteraceae family is extremely large and diverse. Notable medicinal members include:

Geographic Distribution

Safflower has been recorded in 10 countries and territories worldwide, including Afghanistan, China, Germany, Spain, United Kingdom, and others.

Traditional Uses

Safflower has been traditionally used for digestive health, skin and wound care, and urinary tract health, among other applications.

Digestive health.

  • Purgative
  • Laxative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Eruption

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Purgative. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Afghanistan, China, Germany, Spain, United Kingdom, India, Iran, Netherlands, Sweden, United States.

Complete Use Records

CategoryCultural Context
EmmenagogueChina, Elsewhere, Japan, Japan*, Java, Turkey, US
MeaslesElsewhere, Iraq, US
PurgativeChina, Spain, Turkey
AnodyneChina, Turkey
BactericideChina, India
DiureticElsewhere, Mexico
DysmenorrheaChina, Malaya
LaxativeTurkey, US
RheumatismElsewhere, Turkey
SedativeChina, Elsewhere
SudorificTurkey, US
TumorAlgeria, Venezuela
StimulantChina, Elsewhere
AmenorrheaChina
ApoplexyChina
AstringentChina
BloodChina
BruiseChina
DiaphoreticIraq
DiscutientChina
DropsyChina
DyeJapan
EruptionUS(Amerindian)
Food-DyeTurkey
FungicideIndia
GynecopathyJapan
HeartUS
LenitiveChina
RennetTurkey
RubefacientTurkey

Complete Chemical Inventory

CompoundFormulaMW
(E)-11-TRIDECENE-3,5,7,9-TETRAYNE-1,2-DIOL
(E)-2-HEPTENALC₇H₁₂O112.17 Da
(E)-2-HEXENALC₆H₁₀O98.14 Da
(E)-2-HEXENOLC₆H₁₂O100.16 Da
(E)-2-METHYL-2-BUTENALC₅H₈O84.12 Da
(E)-2-PENTENALC₅H₈O84.12 Da
(E)-2-PENTENOLC₅H₁₀O86.13 Da
(E)-BETA-FARNESENEC₁₅H₂₄204.35 Da
(E,E)-2,4-DECADIENALC₁₀H₁₆O152.23 Da
(E,E)-3,11-TRIDECADIENE-5,7,9-TRIYNE-1,2-DIOL
(E,Z)-2,8-DECADIENE-4,6-DIYNE-1-YL-3-METHYLBUTYRATE
(E,Z,E)-1,3,5,11-TRIDECATETRAENE-7,9-DIYNE
(FUNGICIDE)
(Z)-2-HEPTENALC₇H₁₂O112.17 Da
(Z)-2-PENTENOLC₅H₁₀O86.13 Da
(Z)-3-HEXENOLC₆H₁₂O100.16 Da
(Z)-3-HEXENYL-BENZOATE
(Z)-3-HEXENYL-BUTYRATE
(Z)-8-DECENE-4,6-DIYNE-1-YL-3-METHYLBUTYRATE
(Z,Z)-1,8,11-HEPTADECATRIENEC₁₇H₃₀234.4 Da
(Z,Z)-3,11-TRIDECATRIENE-5,7,9-TRIYNE
(Z,Z,Z)-1,8,11,14-HEPTADECATETRAENEC₁₇H₂₈232.4 Da
1,2,3-TRIMETHOXY-5-METHYL-BENZENEC₁₀H₁₄O₃182.22 Da
1-HEPTADECENEC₁₇H₃₄238.5 Da
1-HEXADECENEC₁₆H₃₂224.42 Da
1-PENTADECENEC₁₅H₃₀210.40 Da
1-TRIDECENEC₁₃H₂₆182.35 Da
1-TRIDECENE-3,5,7,9,11-PENTAYNEC₁₃H₆162.19 Da
11E-TRIDECA-1,11-DIENE-3,5,7,9-TETRAYNE
11Z-TRIDECA-1,11-DIENE-3,5,7,9-TETRAYNE

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources