Happy Tree

Botanical Overview

Happy Tree (Camptotheca acuminata) belongs to the Cornaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. This species belongs to the Cornaceae family, a group of flowering plants.

General Description

It is also cultivated in the southern United States. A eudicot, it is a flowering deciduous tree with light gray bark. It can grow to a height of 20 metres (66 ft). Its large, papery leaves are somewhat oval in shape, usually 12 to 28 cm (5 to 10 in) long and 6 to 12 cm (2 to 5 in) wide. The flowers, which bloom from May through July, produce a gray-brown fruit with one seed in September.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Cornaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Happy Tree has been recorded in 10 countries and territories worldwide, including Belgium, Brazil, China, Cuba, Japan, and others.

Traditional Uses

Happy Tree has been traditionally used for immune system support.

Immune system support.

  • Cancer

Immune support involves taking the herb as a decoction or tincture over extended periods. The active compounds stimulate immune cell activity and provide antimicrobial protection.

Active Compounds

Phytochemical research has identified 14 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Belgium, Brazil, China, Cuba, Japan, New Zealand, Taiwan, Ukraine, United States, Unknown.

Complete Use Records

CategoryCultural Context
CancerChina

Complete Chemical Inventory

CompoundFormulaMW
10-HYDROXYCAMPTOTHECINC₂₀H₁₆N₂O₅364.4 Da
11-HYDROXYCAMPTOTHECINC₂₀H₁₆N₂O₅364.4 Da
20-HEXANOYL-10-METHOXYCAMPTOTHECINC₂₇H₂₈N₂O₆476.5 Da
20-HEXANOYLCAMPTOTHECIN
BETULIC-ACIDC₃₀H₄₈O₃456.7 Da
BETULINIC-ACIDC₃₀H₄₈O₃456.7 Da
CAMPTOTHECINC₂₀H₁₆N₂O₄348.4 Da
DEOXYCAMPTOTHECINC₂₀H₁₆N₂O₃332.4 Da
GALLIC-ACIDC₇H₆O₅170.12 Da
QUERCETINC₁₅H₁₀O₇302.23 Da
TRIFOLINC₂₁H₂₀O₁₁448.4 Da
TRIMETHYLELLAGIC-ACID
VENOTERPENE
VINCOSIDE-LACTAMC₂₆H₃₀N₂O₈498.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources