Giant Milkweed

Botanical Overview

Giant Milkweed (Calotropis sp.) is a species in the Asclepiadaceae family. This species belongs to the Asclepiadaceae family, a group of flowering plants. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 30 compounds in this species, suggesting potential medicinal value.

Family Context

The Asclepiadaceae family is widely distributed. Notable medicinal members include:

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Alkaloid: nitrogenous compounds with diverse pharmacological activities

Research Status

Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Further ethnobotanical and pharmacological research may reveal additional therapeutic applications for this species.

ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Complete Chemical Inventory

CompoundFormulaMW
3-O-ACETYL-CALOTROPIN
ALPHA-AMYRINC₃₀H₅₀O426.7 Da
ALPHA-AMYRIN-BENZOATEC₃₇H₅₄O₂530.8 Da
ALPHA-CALOTROPEOL
ALPHA-LACTUCEROLC₃₀H₅₀O426.7 Da
ALPHA-LACTUCERYL-ACETATE
ALPHA-LACTUCERYL-ISOVALERATE
ARABINOSEC₅H₁₀O₅150.13 Da
ASCLEPIIN
ASH
BENZOYLISOLINEOLONE
BENZOYLLINEOLONE
BETA-AMYRINC₃₀H₅₀O426.7 Da
BETA-AMYRIN-BENZOATEC₃₇H₅₄O₂530.8 Da
BETA-CALOTROPEOL
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CALACTINC₂₉H₄₀O₉532.6 Da
CALOTOXINC₂₉H₄₀O₁₀548.6 Da
CALOTROPAGENINC₂₃H₃₂O₆404.5 Da
CALOTROPINC₂₉H₄₀O₉532.6 Da
CALOTROPINE
CAOUTCHOUCC₅H₈68.12 Da
COROGLAUCOGENIN
COROTOXIGENINC₂₃H₃₂O₅388.5 Da
D-GLUCOSAMINEC₆H₁₃NO₅179.17 Da
FATC₁₆H₃₂O₂256.42 Da
FRUGOSIDEC₂₉H₄₄O₉536.7 Da
GIGANTEOL
GIGANTINC₇H₆O₄154.12 Da
GLUCOSEC₆H₁₂O₆180.16 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources