Botanical Overview
Bitter Grass (Calea zacatechichi) belongs to the Asteraceae family. Limited but reliable traditional records indicate this plant has recognized medicinal applications in one or more healing traditions. The daisy family (Asteraceae) is one of the largest plant families, characterized by composite flower heads (capitula) that contain many small florets surrounded by bracts. Plants range from tiny alpine herbs to large tropical trees. The family includes many medicinally important species with bitter compounds and essential oils.

General Description
It is native to Mexico and Central America. Its English language common names include bitter-grass, Mexican calea, and dream herb.
Family Context
The Asteraceae family is extremely large and diverse. Notable medicinal members include:
- Yarrow — 63 documented uses
- Gobo — 63 documented uses
- Mugwort — 55 documented uses
- Sunflower — 52 documented uses
Geographic Distribution
Bitter Grass has been recorded in 7 countries and territories worldwide, including Belize, Guatemala, Honduras, Mexico, El Salvador, and others.
Traditional Uses
Bitter Grass has been traditionally used for digestive health and fever management.
Digestive health.
- Colic
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Fever management.
- Malaria
Febrifuge preparations are typically administered as hot teas to induce perspiration, which helps the body regulate temperature. The patient is kept warm and encouraged to rest while the herb promotes sweating.
Active Compounds
Phytochemical research has identified 16 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Phenolic: antioxidant compounds that neutralize free radicals