Barberry

Botanical Overview

Barberry (Berberis vulgaris) is a flowering plant in the Berberidaceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. The barberry family (Berberidaceae) includes shrubs and herbs with alternate or basal leaves and yellow wood or roots due to alkaloid content. The flowers have six sepals and six petals arranged in whorls, and the fruits are berries or capsules. Many species produce isoquinoline alkaloids like berberine with antimicrobial activity.

General Description

It produces edible but sharply acidic berries, which people in many countries eat as a tart and refreshing fruit.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Berberidaceae family is widely distributed in temperate regions. Notable medicinal members include:

Geographic Distribution

Barberry has been recorded in 10 countries and territories worldwide, including Austria, Switzerland, Germany, Spain, France, and others.

Traditional Uses

Barberry has been traditionally used for digestive health, respiratory conditions, and urinary tract health, among other applications.

Digestive health.

  • Ache(Stomach)
  • Dysentery
  • Dyspepsia
  • Laxative
  • Purgative

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Expectorant

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Alkaloid: nitrogenous compounds with diverse pharmacological activities
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Purgative. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Austria, Switzerland, Germany, Spain, France, United Kingdom, Netherlands, Norway, Sweden, United States.

Complete Use Records

CategoryCultural Context
JaundiceUS, US(Amerindian)
TonicElsewhere, Turkey
Ache(Stomach)US
AlterativeElsewhere
AntisepticTurkey
Cancer(Stomach)France
CholagogueTurkey
DiureticTurkey
DysenteryUS
DyspepsiaUS
ExpectorantTurkey
LaxativeTurkey
MedicineUS(Appalachia)
PurgativeTurkey
UterotonicSpain
FeverUS
HemorrhageUS

Complete Chemical Inventory

CompoundFormulaMW
ALKALOIDS
ALPHA-GLUCAN
ALPHA-TOCOPHEROLC₂₉H₅₀O₂430.7 Da
ALUMINUMAl26.981538 Da
ASCORBIC-ACIDC₆H₈O₆176.12 Da
ASH
BARGUSTANINEC₂₉H₃₄N₂O₇522.6 Da
BERBAMINEC₃₇H₄₀N₂O₆608.7 Da
BERBAMUNINEC₃₆H₄₀N₂O₆596.7 Da
BERBERINEC₂₀H₁₈NO₄+336.4 Da
BERBERRUBINEC₁₉H₁₆NO₄+322.3 Da
BERBERUBINE
BERCULCINE
BERLAMBINEC₂₀H₁₇NO₅351.4 Da
BERVULCINE
BETA-CAROTENEC₄₀H₅₆536.9 Da
BETA-XYLAN
CAFFEIC-ACIDC₉H₈O₄180.16 Da
CALCIUMCa40.08 Da
CAPSANTHINC₄₀H₅₆O₃584.9 Da
CARBOHYDRATES
CHELIDONIC-ACIDC₇H₄O₆184.10 Da
CHLOROGENIC-ACIDC₁₆H₁₈O₉354.31 Da
CHROMIUMCr51.996 Da
CHRYSANTHEMUMXANTHIN
CITRIC-ACIDC₆H₈O₇192.12 Da
COBALTCo58.93319 Da
COLUMBAMINEC₂₀H₂₀NO₄+338.4 Da
COLUMBIANINE
CYANINC₂₇H₃₁O₁₆+611.5 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources