Botanical Overview
Neem (Azadirachta indica) is a flowering plant in the Meliaceae family. This plant has earned a place in traditional medicine through its consistent therapeutic benefits, recorded across multiple cultures. The mahogany family (Meliaceae) includes trees and shrubs with compound leaves and small flowers arranged in branched inflorescences. The fruits are capsules, drupes, or berries. Many species contain limonoid triterpenes with potent insecticidal and antifeedant properties, including azadirachtin from neem.

General Description
It is one of the two species in the genus Azadirachta. It is native to the Indian subcontinent and to parts of Southeast Asia, but is naturalized and grown around the world in tropical and subtropical areas. Its fruits and seeds are the source of neem oil. Nim is a Hindustani noun derived from Sanskrit nimba (निंब).
Family Context
The Meliaceae family is widely distributed. Notable medicinal members include:
- Chinaberry — 54 documented uses
- Andiroba — 17 documented uses
- Jojoban — 16 documented uses
- Cedro Colorado — 6 documented uses
Geographic Distribution
Neem has been recorded in 10 countries and territories worldwide, including Australia, Benin, Brazil, Colombia, India, and others.
Traditional Uses
Neem has been traditionally used for digestive health, skin and wound care, and pain and inflammation, among other applications.
Digestive health.
- Purgative
- Diarrhea
- Laxative
For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.
Skin and wound care.
- Sore
- Ringworm
For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.
Pain and inflammation.
- Rheumatism
For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.
Active Compounds
Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Terpene: aromatic compounds with anti-inflammatory and antimicrobial properties
- Alkaloid: nitrogenous compounds with diverse pharmacological activities