Bitterroot

Also known as: Spreading Dogbane

Botanical Overview

Bitterroot (Apocynum cannabinum) is a flowering plant in the Apocynaceae family. The traditional uses of this species reflect its genuine medicinal value, validated by generations of practical experience. The dogbane family (Apocynaceae) includes herbs, shrubs, vines, and trees with milky sap containing alkaloids and cardiac glycosides. The flowers are typically five-petaled and often showy with a tubular corolla. Many species in this family are highly toxic but also source of important cardiac medications.

General Description

It is poisonous to humans, dogs, cats, and horses. All parts of the plant contain toxic cardiac glycosides that can cause potentially fatal cardiac arrhythmias if ingested. Some Lepidoptera can withstand the toxins and feed on this plant.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Apocynaceae family is primarily tropical and subtropical. Notable medicinal members include:

Geographic Distribution

Bitterroot has been recorded in 10 countries and territories worldwide, including Canada, Switzerland, China, Germany, South Korea, and others.

Traditional Uses

Bitterroot has been traditionally used for digestive health, respiratory conditions, and urinary tract health, among other applications.

Digestive health.

  • Laxative
  • Dysentery
  • Dyspepsia
  • Purgative
  • Vermifuge

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Respiratory conditions.

  • Expectorant
  • Asthma
  • Pneumonia

Respiratory conditions are addressed through steam inhalation of the herb’s vapors or internal use as a warm tea. The hot infusion acts as an expectorant, helping to loosen phlegm and clear congestion. Some traditions combine it with honey for coughs.

Urinary tract health.

  • Diuretic

Urinary tract applications typically involve drinking the herb as a mild tea, which increases urine production and helps flush the urinary system. It may be combined with other demulcent herbs to soothe irritated tissues.

Active Compounds

Phytochemical research has identified 18 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
  • Tannin: astringent compounds that tighten tissues and resist infection
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.
⚠ Caution
Traditional records: This plant has documented uses including Emetic, Purgative, Poison. Self-medication with herbs carries risks including allergic reactions, drug interactions, and toxicity. Only use under the supervision of a qualified healthcare professional.

Distribution and Conservation

Reported distribution: Canada, Switzerland, China, Germany, South Korea, Mexico, Russia, Ukraine, United States, Unknown.

Complete Use Records

CategoryCultural Context
EmeticElsewhere, Turkey, US
ExpectorantElsewhere, Turkey, US
CardiotonicElsewhere, US
DiaphoreticElsewhere, US
DiureticTurkey, US
DropsyTurkey, US
FeverUS, US(Blackfoot)
LaxativeUS, US(Blackfoot)
AlopeciaUS(Blackfoot)
CardiacTurkey
CatharticUS
DysenteryUS
DyspepsiaUS
InflammationUS
IntestineUS
MalariaTurkey
PurgativeUS
VermifugeUS
AsthmaUS
MasticatoryUS(Amerindian)
PneumoniaUS
PoisonUS
SudorificTurkey
TonicUS(Blackfoot)
Condyloma
Wart

Complete Chemical Inventory

CompoundFormulaMW
ALPHA-AMYRINC₃₀H₅₀O426.7 Da
ANDROSTEROLC₁₉H₃₀O274.4 Da
APOCANNOSIDEC₃₀H₄₄O₈532.7 Da
CANNOGENINC₂₃H₃₂O₅388.5 Da
CYMARINC₃₀H₄₄O₉548.7 Da
CYMAROLC₃₀H₄₆O₉550.7 Da
CYNOCANNOSIDE
FATC₁₆H₃₂O₂256.42 Da
HARMALOLC₁₂H₁₂N₂O200.24 Da
HOMOANDROSTEROL
K-STROPHANTHINC₃₉H₆₀O₁₃736.9 Da
LUPEOLC₃₀H₅₀O426.7 Da
OLEANOLIC-ACIDC₃₀H₄₈O₃456.7 Da
P-OXYACETOPHENONEC₈H₈O₂136.15 Da
PROTEIN
RESINC₁₅H₂₄204.35 Da
STROPHANTHIN-CYMAROSIDE
TANNIN

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources