Botanical Overview
Cohoba (Anadenanthera colubrina) is a species in the Fabaceae family. The legume family (Fabaceae) includes trees, shrubs, and herbs that produce pods (legumes) and form nitrogen-fixing root nodules through symbiosis with bacteria. The flowers are typically pea-shaped with five petals. This large family provides food staples, timber, and numerous medicinal species. Phytochemical data for this species are limited at present.
General Description
It grows to 5–20 m (16–66 ft) tall and the trunk is very thorny. The leaves are mimosa-like, up to 30 cm (12 in) in length and they fold up at night. In Argentina, A. colubrina produces flowers from September to December and bean pods from September to July. In Brazil A. colubrina has been given “high priority” conservation status.
Family Context
The Fabaceae family is large and globally distributed. Notable medicinal members include:
- Soybean — 76 documented uses
- Crab’s Eye — 73 documented uses
- Tamarind — 59 documented uses
- Common Indigo — 51 documented uses
Geographic Distribution
Cohoba has been recorded in 10 countries and territories worldwide, including Argentina, Bolivia, Brazil, Colombia, Ecuador, and others.
Active Compounds
Phytochemical research has identified 3 compounds in this species: bufotenine, n,n-dimethyltryptamine, tryptamines.
The identified compounds include the following categories:
- Alkaloid: nitrogenous compounds with diverse pharmacological activities
Research Status
Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.