Mescal

Also known as: Sisal, Hemp Plant, Sisal Agave, Sisal Hemp

Botanical Overview

Mescal (Agave sisalana) belongs to the Agavaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. This species belongs to the Agavaceae family, a group of flowering plants.

General Description

It yields a stiff leaf fiber used in making rope and various other products. The sisal fiber is traditionally used for rope and twine, and has many other uses, including cloth, footwear, hats, bags, carpets, geotextiles, and dartboards. It is also used as fiber reinforcements for composite fiberglass, rubber, and concrete products. Like other agaves, the pith of the leaves can be fermented and distilled to make mezcal.

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Agavaceae family is widely distributed. Notable medicinal members include:

Geographic Distribution

Mescal has been recorded in 10 countries and territories worldwide, including Australia, Spain, Ethiopia, Kenya, Malawi, and others.

Traditional Uses

Mescal has been traditionally used for digestive health, skin and wound care, and reproductive health, among other applications.

Digestive health.

  • Dysentery

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Leprosy

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Reproductive health.

  • Syphilis

In traditional contexts, reproductive health applications typically involve internal preparations such as teas or decoctions. The herb may be taken at specific times during the menstrual cycle.

Active Compounds

Phytochemical research has identified 24 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Sterol: cholesterol-like compounds with anti-inflammatory properties
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Australia, Spain, Ethiopia, Kenya, Malawi, Taiwan, Tanzania, United States, South Africa, Zambia.

Complete Use Records

CategoryCultural Context
DepurativeHaiti, Venezuela
SudorificDominican Republic, Haiti
CicatrizantHaiti
DetergentElsewhere
DysenteryHaiti
LeprosyVenezuela
SyphilisHaiti

Complete Chemical Inventory

CompoundFormulaMW
12-EPIROCKOGENIN
5-ALPHA-PREGNAN-3-BETA,20-BETA-DIOL
ALPHA-CELLULOSEC₁₂H₂₂O₁₁342.30 Da
BARBOURGENINC₂₇H₄₄O₄432.6 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CHLOROGENINC₂₇H₄₄O₄432.6 Da
DELTA-9,10-DEHYDROHECOGENIN
DELTA-9,11-HECOGENIN
DIOSGENINC₂₇H₄₂O₃414.6 Da
GENTROGENINC₂₇H₄₀O₄428.6 Da
GITOGENINC₂₇H₄₄O₄432.6 Da
HAINANGENIN
HECOGENINC₂₇H₄₂O₄430.6 Da
HECONIN
HENTRIACONTAN-1-OLC₃₁H₆₄O452.8 Da
HONGGUANGGENINC₂₈H₄₈O₅464.7 Da
NEOTIGOGENINC₂₇H₄₄O₃416.6 Da
NEOTIGOGENONE
PECTINC₆H₁₀O₇194.14 Da
ROCKOGENINC₂₇H₄₄O₄432.6 Da
SARSAPOGENINC₂₇H₄₄O₃416.6 Da
SISALAGENINC₂₇H₄₂O₄430.6 Da
TIGOGENINC₂₇H₄₄O₃416.6 Da
YAMOGENINC₂₇H₄₂O₃414.6 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources