Agastache rugosa

Botanical Overview

Agastache rugosa belongs to the Lamiaceae family. While not among the most extensively documented medicinal plants, this species has recorded uses that warrant attention from researchers and practitioners. The mint family (Lamiaceae) includes aromatic herbs and shrubs with square stems, opposite leaves, and two-lipped flowers. Many species produce essential oils in glandular trichomes on their leaves and stems. This family is one of the most important sources of culinary and medicinal herbs worldwide.

General Description

Agastache rugosa, also known as wrinkled giant hyssop, Korean mint, purple giant hyssop, Indian mint, Chinese patchouli, or Huoxiang (Chinese: 藿香; pinyin: huòxiāng), is an aromatic herb in the mint family, native to East Asia (China, Japan, Korea, Russian Primorye, Taiwan, India, and Vietnam).

ⓘ Information
Description adapted from Wikipedia (CC BY-SA 4.0).

Family Context

The Lamiaceae family is large and widely distributed. Notable medicinal members include:

  • Basil — 86 documented uses
  • Rosemary — 60 documented uses
  • Agbo — 54 documented uses
  • Sage — 49 documented uses

Geographic Distribution

Agastache rugosa has been recorded in 10 countries and territories worldwide, including Belgium, China, Denmark, Japan, North Korea, and others.

Traditional Uses

Agastache rugosa has been traditionally used for digestive health, skin and wound care, and pain and inflammation, among other applications.

Digestive health.

  • Diarrhea

For digestive complaints, the herb is typically prepared as a tea or decoction taken before meals. The bitter compounds stimulate digestive secretions and improve nutrient absorption. Some traditions use the powdered root or leaves in small doses as a stomachic tonic.

Skin and wound care.

  • Wound

For skin conditions, the fresh or dried plant is applied topically as a poultice, wash, or compress. A strong decoction can be used to clean wounds and sores. The antimicrobial properties help prevent infection while promoting tissue repair.

Pain and inflammation.

  • Ache(Head)
  • Anodyne

For pain and inflammation, preparations are applied both topically as compresses and taken internally. A warm poultice draws blood to the area and promotes healing, while internal preparations address systemic inflammation.

Active Compounds

Phytochemical research has identified 30 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).

The identified compounds include the following categories:

  • Flavonoid: antioxidant compounds that protect cells from oxidative damage
  • Phenolic: antioxidant compounds that neutralize free radicals
  • Sterol: cholesterol-like compounds with anti-inflammatory properties
ⓘ Information
Information on this page is compiled from Dr. Duke’s Phytochemical and Ethnobotanical Databases (USDA ARS), a public domain resource. Consult a healthcare professional before using any herbal preparation.

Distribution and Conservation

Reported distribution: Belgium, China, Denmark, Japan, North Korea, South Korea, Netherlands, Russia, Sweden, United States.

Complete Use Records

CategoryCultural Context
Ache(Head)China
AnginaChina
FeverChina
NauseaChina
WoundChina
AnodyneChina
Cancer(Stomach)China
DiarrheaChina

Complete Chemical Inventory

CompoundFormulaMW
(-)-CARYOPHYLLENEC₁₅H₂₄204.35 Da
3-ALLYL-5-6-DIMETHOXY PHENOL
3-O-ACETYL-OLEANOLIC ALDEHYDE
4-METHOXY-CINNAMIC ALCOHOL
4-METHOXYCINNAMALDEHYDEC₁₀H₁₀O₂162.18 Da
ABIETA-4(18)-8-11-13-TETRAEN-7-ONE
ACACETINC₁₆H₁₂O₅284.26 Da
AGASTACHIN
AGASTACHOSIDEC₂₄H₂₄O₁₁488.4 Da
AGASTANOL
ALPHA-CADINOLC₁₅H₂₆O222.37 Da
ALPHA-HUMULENEC₁₅H₂₄204.35 Da
ALPHA-LIMONENEC₁₀H₁₆136.23 Da
ALPHA-PINENEC₁₀H₁₆136.23 Da
ALPHA-YLANGENEC₁₅H₂₄204.35 Da
ANETHOLEC₁₀H₁₂O148.20 Da
ANISALDEHYDEC₈H₈O₂136.15 Da
BETA OPLOPENTONE
BETA-BOURBONENEC₁₅H₂₄204.35 Da
BETA-CARYOPHYLLENEC₁₅H₂₄204.35 Da
BETA-ELEMENEC₁₅H₂₄204.35 Da
BETA-FARNESENEC₁₅H₂₄204.35 Da
BETA-HUMULENEC₁₅H₂₄204.35 Da
BETA-PINENEC₁₀H₁₆136.23 Da
BETA-SITOSTEROLC₂₉H₅₀O414.7 Da
CALAMENEC₁₅H₂₂202.33 Da
CARYOPHYLLA-4(14)-8(15)-DIEN-5-ALPHA-OL
CARYOPHYLLENEC₁₅H₂₄204.35 Da
CARYOPHYLLENE-OXIDEC₁₅H₂₄O220.35 Da
CARYOPHYLLENOL-IC₁₅H₂₄O220.35 Da

Data from PubChem (NIH/NLM, public domain).


References & Further Reading

External Research Links

Data Sources