Botanical Overview
Sheng ma (Actaea cimicifuga) is a species in the Ranunculaceae family. The buttercup family (Ranunculaceae) includes herbs with alternate or basal leaves and showy flowers with numerous stamens and pistils. Many species contain protoanemonin and other acrid compounds that cause skin irritation. Despite their toxicity, several species have been used in traditional medicine for pain and inflammation. Although comprehensive ethnobotanical records are limited, phytochemical studies have identified 5 compounds in this species, suggesting potential medicinal value.

Family Context
The Ranunculaceae family is widely distributed in temperate regions. Notable medicinal members include:
- Black Cumin — 29 documented uses
- Goldenseal — 29 documented uses
- Bugbane — 28 documented uses
- Black Cohosh — 24 documented uses
Active Compounds
Phytochemical research has identified 5 compounds in this species, including a diverse array of phytochemical classes (see the Complete Chemical Inventory below for the full list).
The identified compounds include the following categories:
- Alkaloid: nitrogenous compounds with diverse pharmacological activities
- Tannin: astringent compounds that tighten tissues and resist infection
Research Status
Although this species has documented phytochemical constituents, its ethnobotanical and clinical documentation remains incomplete. Systematic pharmacological studies are needed to validate the traditional uses attributed to this species.