Before we begin: Histoplasmosis is a disease caused by a fungus (or mold) called Histoplasma. Learn about symptoms and treatment.
This tutorial walks you through everything you need to know about histoplasmosis. We explain it in plain language, step by step, so whether you are a student, a patient, or simply curious, you will come away with a solid understanding.
We cover what it is, why it matters, how it is diagnosed, and what you can do about it. Key facts are called out along the way.
What is histoplasmosis? Histoplasmosis is an infection caused by a fungus called Histoplasma. This fungus is common in the central and eastern United States, especially around the Ohio and Mississippi River valleys. It can also be found in parts of Central and South America, Africa, Asia, and Australia. It lives in the environment, especially in soil that contains large amounts of bat or bird droppings (poop).
How do you get histoplasmosis? You get histoplasmosis by breathing in Histoplasma fungal spores from the air. It usually happens after you have been doing an activity that disturbs the soil, such as farming, construction, and landscaping. Histoplasmosis is not contagious. This means that you cannot get the infection from another person or an animal.
What are the symptoms of histoplasmosis? Most people who breathe in the spores never have any symptoms. If you do get symptoms, they usually start between 3 and 17 days after you breathe in the spores. The symptoms may include:
Fever
Cough
Fatigue
Chills
Headache
Chest pain
Body aches
For most people, the symptoms of histoplasmosis will go away within a few weeks to a month. However, some people can have symptoms that last longer, especially if their infection becomes severe. Certain people are more likely to get a severe infection:
People who have weakened immune systems, for example from:
Having HIV
Having had an organ transplant
Taking medicines which weaken your immune system, such as chemotherapy and steroids
Infants
Adults age 55 and over
Severe histoplasmosis can develop into a long-term lung infection. It can also spread from the lungs to other parts of the body, such as the central nervous system (the brain and spinal cord). This is known as disseminated histoplasmosis.
How is histoplasmosis diagnosed? To find out if you have histoplasmosis, your health care provider:
Will ask about your symptoms and your medical and travel history
Will do a physical exam
Will likely order a blood, urine, or tissue test to look for signs of the fungus
May order a chest x-ray or CT scan of the lungs
What are the treatments for histoplasmosis? For some people, the symptoms of histoplasmosis will go away without treatment. But you will need treatment if you have severe histoplasmosis in the lungs, chronic histoplasmosis, or an infection that has spread to other parts of the body. That treatment would be with prescription antifungal medicines. In some cases, you may need to take the medicines for 3 months to 1 year.
Centers for Disease Control and Prevention
Categories: Infections.
Source: National Institutes of Health — National Institute of Allergy and Infectious Diseases.
Key Takeaways
Understanding histoplasmosis is an important part of taking charge of your health. Here is what to remember:
- Know the signs — Recognizing early symptoms can lead to earlier diagnosis and better outcomes.
- Talk to your provider — If you have concerns or a family history of this condition, bring it up at your next checkup.
- Stay informed — Medical knowledge evolves. Keep learning and asking questions.
- You are not alone — Many people deal with this condition. Support groups and educational resources can help.