Before we begin: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder that is most common in males. Learn about symptoms, diagnosis and treatment.
This tutorial walks you through everything you need to know about g6pd deficiency. We explain it in plain language, step by step, so whether you are a student, a patient, or simply curious, you will come away with a solid understanding.
We cover what it is, why it matters, how it is diagnosed, and what you can do about it. Key facts are called out along the way.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder that is most common in males. About 1 in 10 African American males in the United States has it. G6PD deficiency mainly affects red blood cells, which carry oxygen from the lungs to tissues throughout the body. The most common medical problem it can cause is hemolytic anemia. That happens when red blood cells are destroyed faster than the body can replace them.
If you have G6PD deficiency, you may not have symptoms. Symptoms happen if your red blood cells are exposed to certain chemicals in food or medicine, certain bacterial or viral infections, or stress. They may include:
Paleness
Jaundice
Dark urine
Fatigue
Shortness of breath
Enlarged spleen
Rapid heart rate
A blood test can tell if you have it. Treatments include medicines to treat infection, avoiding substances that cause the problem with red blood cells, and sometimes transfusions.
NIH: National Library of Medicine
Also known as: Glucose-6-phosphate dehydrogenase deficiency.
Related topics: Glucose-6-phosphate Dehydrogenase Deficiency.
Categories: Genetics/Birth Defects.
Key Takeaways
Understanding g6pd deficiency is an important part of taking charge of your health. Here is what to remember:
- Know the signs — Recognizing early symptoms can lead to earlier diagnosis and better outcomes.
- Talk to your provider — If you have concerns or a family history of this condition, bring it up at your next checkup.
- Stay informed — Medical knowledge evolves. Keep learning and asking questions.
- You are not alone — Many people deal with this condition. Support groups and educational resources can help.