Travoprost (5 brand names, 3 dosage forms, 2 routes)
Available dosage forms: SOLUTION/DROPS, IMPLANT, SOLUTION.
Routes of administration: OPHTHALMIC, INTRACAMERAL.
Brand Names
- IDOSE TR
- IZBA
- TRAVATAN
- TRAVATAN Z
- TRAVOPROST
Indications and Usage
Travoprost ophthalmic solution 0.004% (ionic buffered solution) is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Dosage and Administration
The recommended dosage is one drop in the affected eye(s) once daily in the evening. Travoprost ophthalmic solution 0.004% (ionic buffered solution) should not be administered more than once daily since it has been shown that more frequent administration of prostaglandin analogs may decrease the IOP lowering effect. Reduction of the IOP starts approximately 2 hours after the first administration with maximum effect reached after 12 hours. Travoprost ophthalmic solution 0.004% (ionic buffered solution) may be used concomitantly with other topical ophthalmic drug products to lower IOP. If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
Contraindications
None.
Mechanism of Action
Travoprost free acid, a prostaglandin analog is a selective FP prostanoid receptor agonist which is believed to reduce IOP by increasing uveoscleral outflow. The exact mechanism of action is unknown at this time.