Sodium Citrate — Active Pharmaceutical Ingredient

Sodium Citrate is an active pharmaceutical ingredient found in 5 FDA-approved drug products. Forms: SOLUTION, INJECTABLE. Routes: IRRIGATION, INJECTION.

Drug Ingredients A–Z 2 min read
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Sodium Citrate (5 brand names, 2 dosage forms, 2 routes)

Available dosage forms: SOLUTION, INJECTABLE.

Routes of administration: IRRIGATION, INJECTION.

Brand Names

  • BALANCED SALT
  • BSS
  • ISOLYTE E IN DEXTROSE 5% IN PLASTIC CONTAINER
  • ISOLYTE E IN PLASTIC CONTAINER
  • ISOLYTE E W/ DEXTROSE 5% IN PLASTIC CONTAINER

Indications and Usage

Sodium Citrate and Citric Acid Oral Solution USP is an effective alkalinizing agent. It is useful in those conditions where long-term maintenance of an alkaline urine is desirable, and is of value in the alleviation of chronic metabolic acidosis, such as results from chronic renal insufficiency or the syndrome of renal tubular acidosis, especially when the administration of potassium salts is undesirable or contraindicated. This product is also useful for buffering and neutralizing gastric hydrochloric acid quickly and effectively. Sodium Citrate and Citric Acid Oral Solution USP is concentrated, and when administered after meals and before bedtime, allows one to maintain an alkaline urinary pH around the clock, usually without the necessity of a 2 A.M. dose. This product alkalinizes the urine without producing a systemic alkalosis in the recommended dosage. This product is highly palatable, pleasant tasting, and tolerable, even when administered for long periods.

Dosage and Administration

Sodium Citrate and Citric Acid Oral Solution USP should be taken diluted in water, followed by additional water, if desired. SHAKE WELL BEFORE USING.

Contraindications

Patients on sodium-restricted diets or with severe renal impairment.

Adverse Reactions

Sodium Citrate and Citric Acid Oral Solution USP is generally well tolerated, without any unpleasant side effects, when given in recommended doses to patients with normal renal function and urinary output. However, as with any alkalinizing agent, caution must be used in certain patients with abnormal renal mechanisms to avoid development of alkalosis, especially in the presence of hypocalcemia. To report SUSPECTED ADVERSE REACTIONS, contact Pharmaceutical Associates, Inc. at 1-800-845-8210 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch..

Overdosage

Overdosage with sodium salts may cause diarrhea, nausea and vomiting, hypernoia, and convulsions.

⚠ Caution
Medical Disclaimer: This information is for educational purposes only. Always consult a healthcare professional before taking any medication.