Rimegepant Sulfate (1 brand name, 1 dosage form, 1 route)
Available dosage forms: TABLET, ORALLY DISINTEGRATING.
Routes of administration: ORAL.
Brand Names
- NURTEC ODT
Contraindications
NURTEC ODT is contraindicated in patients with a history of hypersensitivity reaction to rimegepant, NURTEC ODT, or any of its components. Reactions have included anaphylaxis and delayed serious hypersensitivity [see Warnings and Precautions (5.1) ].
Adverse Reactions
The following clinically significant adverse reactions are discussed in greater detail in other sections of the labeling: •Hypersensitivity Reactions [see Warnings and Precautions (5.1)] •Hypertension [see Warnings and Precautions (5.2)] •Raynaud’s Phenomenon [see Warnings and Precautions (5.3)]
Mechanism of Action
Rimegepant is a calcitonin gene-related peptide receptor antagonist.
Overdosage
There is limited clinical experience with NURTEC ODT overdosage. Treatment of an overdose of NURTEC ODT should consist of general supportive measures including monitoring of vital signs and observation of the clinical status of the patient. No specific antidote for the treatment of rimegepant overdose is available. Rimegepant is unlikely to be significantly removed by dialysis because of high serum protein binding [see Clinical Pharmacology (12.3)].