Oseltamivir Phosphate (2 brand names, 2 dosage forms, 1 route)
Available dosage forms: CAPSULE, FOR SUSPENSION.
Routes of administration: ORAL.
Brand Names
- OSELTAMIVIR PHOSPHATE
- TAMIFLU
Contraindications
Oseltamivir phosphate for oral suspension is contraindicated in patients with known serious hypersensitivity to oseltamivir or any component of the product. Severe allergic reactions have included anaphylaxis and serious skin reactions including toxic epidermal necrolysis, Stevens-Johnson Syndrome, and erythema multiforme [see Warnings and Precautions (5.1)].
Adverse Reactions
The following serious adverse reactions are discussed below and elsewhere in the labeling: Serious skin and hypersensitivity reactions [see Warnings and Precautions (5.1)] Neuropsychiatric events [see Warnings and Precautions (5.2)]
Mechanism of Action
Oseltamivir is an antiviral drug with activity against influenza virus [see Microbiology (12.4)].
Overdosage
Reports of overdoses with oseltamivir phosphate have been received from clinical trials and during postmarketing experience. In the majority of cases reporting overdose, no adverse reactions were reported. Adverse reactions reported following overdose were similar in nature to those observed with therapeutic doses of oseltamivir phosphate[see Adverse Reactions (6)].