Mupirocin (3 brand names, 1 dosage form, 1 route)
Available dosage forms: OINTMENT.
Routes of administration: TOPICAL.
Brand Names
- BACTROBAN
- CENTANY
- MUPIROCIN
Indications and Usage
Mupirocin Ointment USP, 2% is indicated for the topical treatment of impetigo due to susceptible isolates of Staphylococcus aureus (S. aureus)and Streptococcus pyogenes (S. pyogenes).
Dosage and Administration
For Topical Use Only. Apply a small amount of Mupirocin Ointment USP, 2%, with a cotton swab or gauze pad, to the affected area 3 times daily for up to 10 days. Cover the treated area with gauze dressing if desired. Re-evaluate patients not showing a clinical response within 3 to 5 days. Mupirocin Ointment USP, 2% is not for intranasal, ophthalmic, or other mucosal use [ see Warnings and Precautions (5.2, 5.6)]. Do not apply Mupirocin Ointment USP, 2% concurrently with any other lotions, creams, or ointments [ see Clinical Pharmacology (12.3)].
Contraindications
Mupirocin Ointment USP, 2% is contraindicated in patients with known hypersensitivity to mupirocin or any of the excipients of Mupirocin Ointment USP, 2%.
Adverse Reactions
The following adverse reactions are discussed in more detail in other sections of the labeling: Severe Allergic Reactions [ see Warnings and Precautions (5.1)] Eye Irritation [ see Warnings and Precautions (5.2)] Local Irritation [ see Warnings and Precautions (5.3)] Clostridium difficile-Associated Diarrhea [ see Warnings and Precautions (5.4)]
Mechanism of Action
Mupirocin is an RNA synthetase inhibitor antibacterial [ see Microbiology (12.4)].