Mupirocin Calcium (2 brand names, 2 dosage forms, 2 routes)
Available dosage forms: CREAM, OINTMENT.
Routes of administration: TOPICAL, NASAL.
Brand Names
- BACTROBAN
- MUPIROCIN
Related Health Topics
Indications and Usage
Mupirocin Cream USP, 2% is indicated for the treatment of secondarily infected traumatic skin lesions (up to 10 cm in length or 100 cm 2in area) due to susceptible isolates of Staphylococcus aureus (S. aureus)and Streptococcus pyogenes (S. pyogenes).
Dosage and Administration
For Topical Use Only. Apply a small amount of mupirocin cream, with a cotton swab or gauze pad, to the affected area 3 times daily for 10 days. Cover the treated area with gauze dressing if desired. Re-evaluate patients not showing a clinical response within 3 to 5 days. Mupirocin cream is not for intranasal, ophthalmic, or other mucosal use [see Warnings and Precautions (5.2, 5.6)] . Do not apply mupirocin cream concurrently with any other lotions, creams or ointments [see Clinical Pharmacology (12.3)] .
Contraindications
Mupirocin cream is contraindicated in patients with known hypersensitivity to mupirocin or any of the excipients of mupirocin cream.
Adverse Reactions
The following adverse reactions are discussed in more detail in other sections of the labeling: Severe Allergic Reactions [see Warnings and Precautions (5.1)] Eye Irritation [see Warnings and Precautions (5.2)] Local Irritation [see Warnings and Precautions (5.3)] Clostridium difficile-Associated Diarrhea [see Warnings and Precautions (5.4)]
Mechanism of Action
Mupirocin is an RNA synthetase inhibitor antibacterial [see Microbiology (12.4)] .