Meloxicam (9 brand names, 6 dosage forms, 3 routes)
Available dosage forms: TABLET, CAPSULE, SUSPENSION, SOLUTION, SOLUTION, EXTENDED RELEASE, TABLET, ORALLY DISINTEGRATING.
Routes of administration: ORAL, INTRAVENOUS, PERIARTICULAR.
Brand Names
- ANJESO
- MELOXICAM
- MOBIC
- QAMZOVA
- QMIIZ ODT
- SYMBRAVO
- VIVLODEX
- XIFYRM
- ZYNRELEF KIT
Mechanism of Action
Meloxicam has analgesic, anti-inflammatory, and antipyretic properties. The mechanism of action of Meloxicam, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Meloxicam is a potent inhibitor of prostaglandin synthesis in vitro. Meloxicam concentrations reached during therapy have produced in vivo effects. Prostaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain in animal models. Prostaglandins are mediators of inflammation. Because meloxicam is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues.