Meclizine Hydrochloride (2 brand names, 2 dosage forms, 1 route)
Available dosage forms: TABLET, TABLET, CHEWABLE.
Routes of administration: ORAL.
Brand Names
- ANTIVERT
- MECLIZINE HYDROCHLORIDE
Indications and Usage
Meclizine hydrochloride is indicated for the treatment of vertigo associated with diseases affecting the vestibular system in adults.
Contraindications
Meclizine hydrochloride is contraindicated in patients with a hypersensitivity to meclizine or any of the inactive ingredients [see Adverse Reactions (6)and Description (11)].
Adverse Reactions
The following adverse reactions associated with the use of meclizine hydrochloride were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Anaphylactic reaction, drowsiness, dry mouth, headache, fatigue, and vomiting. On rare occasions blurred vision has been reported.
Mechanism of Action
The precise mechanism by which meclizine exerts its therapeutic effect is unknown but is presumed to involve antagonism of the histamine H1 receptor.