Gramicidin — Active Pharmaceutical Ingredient

Gramicidin is an active pharmaceutical ingredient found in 4 FDA-approved drug products. Forms: SOLUTION/DROPS. Routes: OPHTHALMIC.

This content is for informational purposes only. Always consult a healthcare professional.

Gramicidin (4 brand names, 1 dosage form, 1 route)

Available dosage forms: SOLUTION/DROPS.

Routes of administration: OPHTHALMIC.

Brand Names

  • NEO-POLYCIN
  • NEOMYCIN AND POLYMYXIN B SULFATES AND GRAMICIDIN
  • NEOMYCIN SULFATE AND POLYMYXIN B SULFATE GRAMICIDIN
  • NEOSPORIN

Indications and Usage

Neomycin and polymyxin B sulfates and gramicidin ophthalmic solution is indicated for the topical treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria. Such infections encompass conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.

Dosage and Administration

Instill one or two drops into the affected eye every 4 hours for 7 to 10 days. In severe infections, dosage may be increased to as much as two drops every hour.

Contraindications

This product is contraindicated in those persons who have shown hypersensitivity to any of its components.

Adverse Reactions

Adverse reactions have occurred with the anti-infective components of this product. The exact incidence is not known. Reactions occurring most often are allergic reactions including itching, swelling, and conjunctival erythema (see WARNINGS ). More serious hypersensitivity reactions, including anaphylaxis, have been reported rarely. Local irritation on instillation has also been reported. To report SUSPECTED ADVERSE REACTIONS, contact Bausch & Lomb Incorporated at 1-800-553-5340 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

⚠ Caution
Medical Disclaimer: This information is for educational purposes only. Always consult a healthcare professional before taking any medication.