Flurbiprofen Sodium — Active Pharmaceutical Ingredient

Flurbiprofen Sodium is an active pharmaceutical ingredient found in 2 FDA-approved drug products. Forms: SOLUTION/DROPS. Routes: OPHTHALMIC.

This content is for informational purposes only. Always consult a healthcare professional.

Flurbiprofen Sodium (2 brand names, 1 dosage form, 1 route)

Available dosage forms: SOLUTION/DROPS.

Routes of administration: OPHTHALMIC.

Brand Names

  • FLURBIPROFEN SODIUM
  • OCUFEN

Indications and Usage

Flurbiprofen sodium ophthalmic solution is indicated for the inhibition of intraoperative miosis.

Dosage and Administration

A total of four (4) drops of flurbiprofen sodium ophthalmic solution should be administered by instilling one (1) drop approximately every 1/2 hour beginning 2 hours before surgery.

Contraindications

Flurbiprofen sodium ophthalmic solution is contraindicated in individuals who are hypersensitive to any components of the medication.

Adverse Reactions

Transient burning and stinging upon instillation and other minor symptoms of ocular irritation have been reported with the use of flurbiprofen sodium ophthalmic solution. Other adverse reactions reported with the use of flurbiprofen sodium ophthalmic solution include: fibrosis, hyphema, miosis, mydriasis, and ocular hyperemia. Increased bleeding tendency of ocular tissues in conjunction with ocular surgery has also been reported (see Warnings). To report SUSPECTED ADVERSE REACTIONS, contact Bausch & Lomb Incorporated at 1-800-553-5340 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Drug Interactions

Interaction of flurbiprofen sodium ophthalmic solution with other topical ophthalmic medications has not been fully investigated. Although clinical studies with acetylcholine chloride and animal studies with acetylcholine chloride or carbachol revealed no interference, and there is no known pharmacological basis for an interaction, there have been reports that acetylcholine chloride and carbachol have been ineffective when used in patients treated with flurbiprofen sodium ophthalmic solution.

Overdosage

Overdosage will not ordinarily cause acute problems. If accidentally ingested, drink fluids to dilute.

⚠ Caution
Medical Disclaimer: This information is for educational purposes only. Always consult a healthcare professional before taking any medication.