Ferric Pyrophosphate Citrate (2 brand names, 2 dosage forms, 1 route)
Available dosage forms: POWDER, SOLUTION.
Routes of administration: INTRAVENOUS.
Brand Names
- TRIFERIC
- TRIFERIC AVNU
Indications and Usage
Triferic is an iron replacement product indicated for the replacement of iron to maintain hemoglobin in adult patients with hemodialysis-dependent chronic kidney disease (HDD-CKD).
Contraindications
None
Adverse Reactions
The following adverse reactions are described below and elsewhere in the labeling: Hypersensitivity reactions [ see Warnings and Precautions (5.1) ].
Mechanism of Action
Triferic contains iron in the form of ferric pyrophosphate citrate and is added to hemodialysate solution to be administered to patients by transfer across the dialyzer membrane. Iron delivered into the circulation binds to transferrin for transport to erythroid precursor cells to be incorporated into hemoglobin.