Efinaconazole (2 brand names, 1 dosage form, 1 route)
Available dosage forms: SOLUTION.
Routes of administration: TOPICAL.
Brand Names
- EFINACONAZOLE
- JUBLIA
Indications and Usage
JUBLIA (efinaconazole) topical solution, 10% is an azole antifungal indicated for the topical treatment of onychomycosis of the toenail(s) due to Trichophyton rubrum and Trichophyton mentagrophytes.
Dosage and Administration
Apply JUBLIA to affected toenails once daily for 48 weeks, using the integrated flow-through brush applicator. When applying JUBLIA, ensure the toenail, the toenail folds, toenail bed, hyponychium, and the undersurface of the toenail plate, are completely covered. JUBLIA is for topical use only and not for oral, ophthalmic, or intravaginal use.
Contraindications
None.
Drug Interactions
In vitro studies have shown that JUBLIA, at therapeutic concentrations, neither inhibits nor induces cytochrome P450 (CYP450) enzymes.
Mechanism of Action
JUBLIA topical solution is an azole antifungal [see Clinical Pharmacology (12.4) ].