Edaravone (3 brand names, 4 dosage forms, 4 routes)
Available dosage forms: SUSPENSION, SOLUTION, INJECTION, INJECTABLE.
Routes of administration: ORAL, INTRAVENOUS, SOLUTION, INJECTION.
Brand Names
- EDARAVONE
- RADICAVA
- RADICAVA ORS
Indications and Usage
Edaravone injection is indicated for the treatment of amyotrophic lateral sclerosis (ALS).
Contraindications
Edaravone injection is contraindicated in patients with a history of hypersensitivity to edaravone or any of the inactive ingredients in this product. Hypersensitivity reactions and anaphylactic reactions have occurred [see WARNINGS AND PRECAUTIONS ( 5.1, 5.2)] .
Adverse Reactions
The following serious adverse reactions are described elsewhere in the labeling: Hypersensitivity Reactions [see WARNINGS AND PRECAUTIONS (5.1)] Sulfite Allergic Reactions [see WARNINGS AND PRECAUTIONS (5.2)]
Mechanism of Action
The mechanism by which edaravone injection exerts its therapeutic effect in patients with ALS is unknown.