Dextrose (338 brand names, 3 dosage forms, 5 routes)
Available dosage forms: INJECTABLE, SOLUTION, EMULSION.
Routes of administration: INJECTION, INTRAPERITONEAL, IRRIGATION, INTRATHECAL, INTRAVENOUS.
Brand Names
- ALCOHOL 5% AND DEXTROSE 5%
- AMINOSYN 3.5% W/ DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN 3.5% W/ DEXTROSE 5% IN PLASTIC CONTAINER
- AMINOSYN 4.25% W/ DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN II 3.5% IN DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN II 3.5% IN DEXTROSE 5% IN PLASTIC CONTAINER
- AMINOSYN II 3.5% M IN DEXTROSE 5% IN PLASTIC CONTAINER
- AMINOSYN II 3.5% W/ ELECTROLYTES IN DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN II 3.5% W/ ELECTROLYTES IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER
- AMINOSYN II 4.25% IN DEXTROSE 10% IN PLASTIC CONTAINER
- AMINOSYN II 4.25% IN DEXTROSE 20% IN PLASTIC CONTAINER
- AMINOSYN II 4.25% IN DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN II 4.25% M IN DEXTROSE 10% IN PLASTIC CONTAINER
- AMINOSYN II 4.25% W/ ELECT AND ADJUSTED PHOSPHATE IN DEXTROSE 10% IN PLASTIC CONTAINER
- AMINOSYN II 4.25% W/ ELECTROLYTES IN DEXTROSE 20% W/ CALCIUM IN PLASTIC CONTAINER
- AMINOSYN II 4.25% W/ ELECTROLYTES IN DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN II 4.25% W/ ELECTROLYTES IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER
- AMINOSYN II 5% IN DEXTROSE 25% IN PLASTIC CONTAINER
- AMINOSYN II 5% W/ ELECTROLYTES IN DEXTROSE 25% W/ CALCIUM IN PLASTIC CONTAINER
- BSS PLUS …and 318 more
Indications and Usage
Dextrose Injection is indicated as source of water and calories.
Contraindications
The use of Dextrose Injection is contraindicated in patients with: • Clinically significant hyperglycemia [see Warnings and Precautions (5.1) ]. • Known hypersensitivity to dextrose [see Warnings and Precautions (5.2) ].
Adverse Reactions
The following adverse reactions associated with the use of dextrose injection were identified in clinical trials or postmarketing reports. Because these reactions were reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency, reliably, or to establish a causal relationship to drug exposure. The following clinically significant adverse reactions are described elsewhere in the labeling: •Hyperglycemia and hyperosmolar hyperglycemic state [see Warnings and Precautions (5.1)] • Hypersensitivity Reactions: anaphylaxis, pruritis, bronchospasm, cyanosis, angioedema, hypotension, pyrexia, chills, and rash [see Warnings and Precautions (5.2)] • Infusion Site Reactions: infusion site phlebitis, infusion site erythema, vein damage and thrombosis [see Warnings and Precautions (5.3)] •Hyponatremia and hyponatremic encephalopathy [see Warnings and Precautions (5.4)] •Electrolyte imbalance, fluid overload and hypervolemia [see Warnings and Precautions (5.5)] •Refeeding syndrome [see Warnings and Precautions (5.6)]
Mechanism of Action
Dextrose is oxidized to carbon dioxide and water, yielding energy.
Overdosage
An increased infusion rate of Dextrose Injection or administration of dextrose solutions can cause hyperglycemia, hyperosmolality, and adverse effects on water and electrolyte balance [see Warnings and Precautions (5.1, 5.5)]. Severe hyperglycemia and severe dilutional hyponatremia, and their complications, can be fatal. Discontinue infusion, reduce dose and institute appropriate corrective measures such as administration of exogenous insulin. Discontinue infusion and institute appropriate corrective measures in the event of overhydration or solute overload during therapy, with particular attention to CNS, respiratory and cardiovascular systems. If over-exposure occurs, call your Poison Control Center at 1-800-222-1222 for current information on the management of poisoning or overdosage.