Cefuroxime (1 brand name, 1 dosage form, 1 route)
Available dosage forms: Injectable.
Routes of administration: Injection.
Brand Names
- CEFUROXIME
Contraindications
Cefuroxime axetil tablets are contraindicated in patients with a known hypersensitivity (e.g., anaphylaxis) to cefuroxime axetil tablets or to other β-lactam antibacterial drugs (e.g., penicillins and cephalosporins).
Adverse Reactions
The following serious and otherwise important adverse reaction is described in greater detail in the Warnings and Precautions section of the label: Anaphylactic Reactions [see Warnings and Precautions (5.1)].
Mechanism of Action
Cefuroxime axetil is an antibacterial drug [see Microbiology (12.4)].
Overdosage
Overdosage of cephalosporins can cause cerebral irritation leading to convulsions or encephalopathy. Serum levels of cefuroxime can be reduced by hemodialysis and peritoneal dialysis.