Cefazolin Sodium — Active Pharmaceutical Ingredient

Cefazolin Sodium is an active pharmaceutical ingredient found in 8 FDA-approved drug products. Forms: INJECTABLE, POWDER, SOLUTION. Routes: INJECTION, INTRAVENOUS.

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Cefazolin Sodium (8 brand names, 3 dosage forms, 2 routes)

Available dosage forms: INJECTABLE, POWDER, SOLUTION.

Routes of administration: INJECTION, INTRAVENOUS.

Brand Names

  • ANCEF
  • ANCEF IN DEXTROSE 5% IN PLASTIC CONTAINER
  • ANCEF IN PLASTIC CONTAINER
  • ANCEF IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
  • CEFAZOLIN AND DEXTROSE
  • CEFAZOLIN IN DEXTROSE
  • CEFAZOLIN SODIUM
  • KEFZOL

Adverse Reactions

The following serious adverse reactions to Cefazolin in Dextrose Injection are described below and elsewhere in the labeling: •Hypersensitivity Reactions to Cefazolin, Cephalosporins, Penicillins, or Other Beta-lactams [see Warnings and Precautions (5.1) ] •Seizures in Patients with Renal Impairment [see Warnings and Precautions (5.2) ] • Clostridioides difficile-associated Diarrhea [see Warnings and Precautions (5.3)]

Drug Interactions

The renal excretion of cefazolin is inhibited by probenecid. Co-administration of probenecid with Cefazolin in Dextrose Injection is not recommended.

Mechanism of Action

Cefazolin is an antibacterial drug [see Microbiology (12.4) ].

Overdosage

Accidental overdosage resulting in seizures may occur in patients with renal impairment who receive doses greater than the recommended dosage of Cefazolin in Dextrose Injection [see Warnings and Precautions (5.2)]. If seizures associated with accidental overdosage occur, discontinue Cefazolin in Dextrose Injection and give supportive treatment.

⚠ Caution
Medical Disclaimer: This information is for educational purposes only. Always consult a healthcare professional before taking any medication.