Cannabidiol (1 brand name, 1 dosage form, 1 route)
Available dosage forms: SOLUTION.
Routes of administration: ORAL.
Brand Names
- EPIDIOLEX
Indications and Usage
EPIDIOLEX is indicated for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in patients 1 year of age and older.
Contraindications
EPIDIOLEX is contraindicated in patients with a history of hypersensitivity to cannabidiol or any of the ingredients in the product [see Description (11) and Warnings and Precautions (5.4)].
Adverse Reactions
The following important adverse reactions are described elsewhere in labeling: •Hepatic Injury [see Warnings and Precautions (5.1)] •Somnolence and Sedation [see Warnings and Precautions (5.2)] •Suicidal Behavior and Ideation [see Warnings and Precautions (5.3)] •Hypersensitivity Reactions [see Warnings and Precautions (5.4)] •Withdrawal of Antiepileptic Drugs [see Warnings and Precautions (5.5)]
Mechanism of Action
The precise mechanisms by which EPIDIOLEX exerts its anticonvulsant effect in humans are unknown. Cannabidiol does not appear to exert its anticonvulsant effects through interaction with cannabinoid receptors.