Aztreonam (5 brand names, 3 dosage forms, 3 routes)
Available dosage forms: INJECTABLE, FOR SOLUTION, POWDER.
Routes of administration: INJECTION, INHALATION, INTRAVENOUS.
Brand Names
- AZACTAM
- AZACTAM IN PLASTIC CONTAINER
- AZTREONAM
- CAYSTON
- EMBLAVEO
Contraindications
EMBLAVEO is contraindicated in patients with known hypersensitivity to the components of EMBLAVEO (aztreonam and avibactam) [see Warnings and Precautions ( 5.1 )].
Adverse Reactions
The following adverse reactions are discussed in greater detail in the Warnings and Precautions section: Hypersensitivity Reactions [see Warnings and Precautions ( 5.1 )] Serious Skin Disorders [see Warnings and Precautions ( 5.2 )] Hepatic Adverse Reactions [see Warnings and Precautions ( 5.3 )] Clostridioides Difficile-Associated Diarrhea [see Warnings and Precautions ( 5.4 )]
Mechanism of Action
EMBLAVEO is an antibacterial drug [see Microbiology ( 12.4 )].
Overdosage
There is no information on the clinical signs and symptoms associated with an overdose of EMBLAVEO. Aztreonam and avibactam can be partially removed by hemodialysis [see Clinical Pharmacology ( 12.3 )]. No clinical information is available on the use of hemodialysis to treat EMBLAVEO overdosage.