Azithromycin (4 brand names, 7 dosage forms, 3 routes)
Available dosage forms: TABLET, INJECTABLE, FOR SUSPENSION, CAPSULE, FOR SUSPENSION, EXTENDED RELEASE, SOLUTION, SOLUTION/DROPS.
Routes of administration: ORAL, INJECTION, OPHTHALMIC.
Brand Names
- AZASITE
- AZITHROMYCIN
- ZITHROMAX
- ZMAX
Indications and Usage
Azithromycin is a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Recommended dosages and durations of therapy in adult and pediatric patient populations vary in these indications [see Dosage and Administration (2)].
Adverse Reactions
The following clinically significant adverse reactions are described elsewhere in labeling: •Hypersensitivity [see Warnings and Precautions (5.1)] •Hepatotoxicity [see Warnings and Precautions (5.2)] •Infantile Hypertrophic Pyloric Stenosis (IHPS) [see Warnings and Precautions (5.3)] •QT Prolongation [see Warnings and Precautions (5.4)] •Cardiovascular Death [see Warnings and Precautions (5.5)] •Clostridioides difficile-Associated Diarrhea (CDAD) [see Warnings and Precautions ( 5.6 )] •Exacerbation of Myasthenia Gravis [see Warnings and Precautions (5.7)]
Mechanism of Action
Azithromycin is a macrolide antibacterial drug [see Microbiology (12.4)].
Overdosage
Adverse reactions experienced at higher than recommended doses were similar to those seen at normal doses particularly nausea, diarrhea, and vomiting. In the event of overdosage, general symptomatic and supportive measures are indicated as required.