Alcaftadine — Active Pharmaceutical Ingredient

Alcaftadine (2 brand names, 1 dosage form, 1 route)

Available dosage forms: SOLUTION/DROPS.

Routes of administration: OPHTHALMIC.

Brand Names

• ALCAFTADINE
• LASTACAFT

Indications and Usage

LASTACAFT® is an H1 histamine receptor antagonist indicated for the prevention of itching associated with allergic conjunctivitis.

Dosage and Administration

Instill one drop in each eye once daily. If more than 1 topical ophthalmic medicinal product is being used, each one should be administered at least 5 minutes apart.

Contraindications

LASTACAFT® is contraindicated in patients with hypersensitivity to any component in the product.

Mechanism of Action

Alcaftadine is an H1 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. Decreased chemotaxis and inhibition of eosinophil activation has also been demonstrated.