Acoltremon — Active Pharmaceutical Ingredient

Acoltremon is an active pharmaceutical ingredient found in 1 FDA-approved drug product. Forms: SOLUTION/DROPS. Routes: OPHTHALMIC.

Drug Ingredients A–Z 1 min read
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Acoltremon (1 brand name, 1 dosage form, 1 route)

Available dosage forms: SOLUTION/DROPS.

Routes of administration: OPHTHALMIC.

Brand Names

  • TRYPTYR

Indications and Usage

TRYPTYR is indicated for the treatment of the signs and symptoms of dry eye disease.

Contraindications

None.

Mechanism of Action

Studies in animals suggest that acoltremon, the active substance in TRYPTYR, is an agonist of transient receptor potential melastatin 8 (TRPM8) thermoreceptors. TRPM8 thermoreceptor stimulation has been shown to activate trigeminal nerve signaling leading to increased basal tear production. The exact mechanism of action for TRYPTYR in dry eye disease is unknown.

⚠ Caution
Medical Disclaimer: This information is for educational purposes only. Always consult a healthcare professional before taking any medication.