Source: ClinicalTrials.gov — U.S. National Library of Medicine — A database of privately and publicly funded clinical studies conducted around the world (U.S. National Library of Medicine, public domain).
This page lists clinical trials related to Toe Injuries and Disorders from the ClinicalTrials.gov database.
Trial Summary
- Total studies: 11
- Recruiting: 2
- Active, not recruiting: 0
- Completed: 8
- Other: 1
Results are refreshed periodically and may not reflect the most current information available from ClinicalTrials.gov.
Recruiting Trials
NCT05555459 — Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation
| Status | Recruiting |
| Phase | N/A |
| Sponsor | Inion Oy |
| Enrollment | 125 |
| Study Type | INTERVENTIONAL |
| Conditions | Medial Malleolus Fracture; Lisfranc Injury; Lisfranc Fracture; Talus Fracture; Calcaneus Fracture |
| Interventions |
The study in question is a post market clinical follow up (PMCF) study to evaluate the safety and performance of bioabsorbable headless compression screw Inion CompressOn in selected fracture, osteotomy and arthrodeses operations of the foot and ankle. The study recruits 125 adult patients who meet the acceptance criteria. The follow-up time for each study patient is 4 years. The study is a sin…
NCT07090057 — The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
| Status | Recruiting |
| Phase | N/A |
| Sponsor | University of Alberta |
| Enrollment | 42 |
| Study Type | INTERVENTIONAL |
| Conditions | Idiopathic Toe Walking; Cerebral Palsy; Hereditary Spastic Paraparesis; Traumatic Brain Injury; Spinal Cord Injury |
| Interventions | ; |
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk. If not treated, children with ankle equinus frequently experience reduced function and long-term foot problems, such as pain. Currently, treatment options include surgery or Botulinum toxin (BoNTA) injection into the large calf muscl…
Completed Trials
NCT00969969 — A Study to Evaluate the Effectiveness and Safety of an Implant in the Treatment of Osteoarthritis of the Great Toe
| Status | Completed |
| Phase | Phase 3 |
| Sponsor | Cartiva, Inc. |
| Enrollment | 236 |
| Study Type | INTERVENTIONAL |
| Conditions | Osteoarthritis of First Metatarsalphalangeal Joint |
| Interventions | ; |
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the great toe.
NCT02978573 — Post Approval Study to Evaluate the Effectiveness and Safety of Cartiva Implant in the Treatment of OA of the Great Toe
| Status | Completed |
| Phase | Phase 3 |
| Sponsor | Cartiva, Inc. |
| Enrollment | 135 |
| Study Type | INTERVENTIONAL |
| Conditions | Osteoarthritis of First Metatarsalphalangeal Joint |
| Interventions |
Evaluate and confirm the long-term safety and effectiveness of the Cartiva SCI implant established by the pivotal trial.
NCT03843177 — Association of Ingrown Toenails With Flat Foot, Hallux Abducto Valgus and Hallux Limitus
| Status | Completed |
| Phase | N/A |
| Sponsor | Chinese University of Hong Kong |
| Enrollment | 41 |
| Study Type | OBSERVATIONAL |
| Conditions | Ingrown Toe Nail; Flat Foot; Hallux Abductovalgus; Hallux Limitus |
| Interventions |
This study will have implications for any healthcare professionals who routinely manage ingrown toenails. Although different conservative and surgical treatment have been suggested, the recurrent rate is still high ranging from 20% to 30%. The objective of this study was to investigate the association of ingrown toenail (IGTN) with flat foot, hallux abducto valgus (HAV) and hallux limitus (HL),…
NCT03934281 — Study of the Value of Using a Honey Dressing Compared to the Use of a Standard Dressing on the Toe Amputation Wound in the Diabetic Patient
| Status | Completed |
| Phase | N/A |
| Sponsor | Centre Hospitalier Metropole Savoie |
| Enrollment | 24 |
| Study Type | INTERVENTIONAL |
| Conditions | Diabete Mellitus; Amputation; Amputation Wound; Toe (Toes); Wound |
| Interventions | ; |
Numerous scientific publications in France and internationally have described the healing, anti-bacterial, anti-oxidant, anti-inflammatory and immuno-modulating properties of honey.
Honey is effective in the management of many infected or uninfected post-surgical wounds.
This study focuses on post surgical wounds after toe amputation in diabetic patients.
The main objective of this study is …
NCT05094687 — Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
| Status | Completed |
| Phase | N/A |
| Sponsor | Jinnah Postgraduate Medical Centre |
| Enrollment | 1206 |
| Study Type | OBSERVATIONAL |
| Conditions | Cutaneous Manifestations; Skin Manifestations; COVID-19; COVID-19 Pneumonia; COVID-19 Pandemic |
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019. Pulmonary health has been the main focus of studies of COVID-19, current articles show that cutaneous signs appear in COVID-19 patients, their identification may be vital to early diagnosis and lead to possible…
NCT04229563 — Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
| Status | Completed |
| Phase | N/A |
| Sponsor | Angiodynamics, Inc. |
| Enrollment | 102 |
| Study Type | OBSERVATIONAL |
| Conditions | Infrainguinal Peripheral Artery Disease; Peripheral Arterial Disease; PAD |
| Interventions |
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term) of the AURYON Atherectomy System, within the initial launch phase of the product in the market.
NCT04771741 — Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study
| Status | Completed |
| Phase | N/A |
| Sponsor | Prisma Health-Midlands |
| Enrollment | 72 |
| Study Type | OBSERVATIONAL |
| Conditions | Bunion of Unspecified Foot; Bunionette of Unspecified Foot; Hammertoe; Ankle Fractures; Achilles Tendon Surgery |
| Interventions | ; ; |
Orthopedic surgeons frequently prescribe and over-prescribe narcotic pain medications during the postoperative period, despite the ongoing opioid crisis in the United States. While opioid-free multimodal pathways have shown promising results, there remains a lack of published literature evaluating opiate-free multimodal pain protocols for elective outpatient foot and ankle surgeries. This study…
NCT06054659 — CGM and DFU Healing Post-discharge
| Status | Completed |
| Phase | N/A |
| Sponsor | Emory University |
| Enrollment | 116 |
| Study Type | INTERVENTIONAL |
| Conditions | Diabetic Foot; Diabetes Type 2 With Diabetic Ulcer of Toe, Skin Breakdown |
| Interventions | ; ; |
The purpose of this study is to look at the benefits of using a Continuous Glucose Monitoring (CGM) system compared with standard-of-care testing for patients with type 2 diabetes and diabetic foot ulcers (DFU) and how this will improve wound healing.
The CGM system allows medical staff and patients with diabetes to monitor and make treatment decisions to improve glucose control, without the n…
Other (Unknown)
NCT05855980 — Toe Amputations in Patients With Diabetes
| Status | Unknown |
| Phase | N/A |
| Sponsor | Tampere University Hospital |
| Enrollment | 102 |
| Study Type | INTERVENTIONAL |
| Conditions | Diabetic Foot; Infections; Amputation |
| Interventions |
This study is a randomized controlled trial (RCT) to evaluate outcome after toe amputation due to diabetic foot infection. Aim of this RCT is to evaluate wound healing and functional outcome based, whether wound is closed or left open. As a part of this study, emerging technology of thermal imaging is evaluated as a possible tool to predict complication after amputation.