Source: ClinicalTrials.gov — U.S. National Library of Medicine — A database of privately and publicly funded clinical studies conducted around the world (U.S. National Library of Medicine, public domain).

This page lists clinical trials related to How to Prevent Heart Disease from the ClinicalTrials.gov database.

Trial Summary

Total studies: 8
Recruiting: 1
Active, not recruiting: 1
Completed: 2
Other: 4

Results are refreshed periodically and may not reflect the most current information available from ClinicalTrials.gov.

Recruiting Trials

NCT06062394 — Penn Medicine Healthy Heart


Status	Recruiting
Phase	N/A
Sponsor	University of Pennsylvania
Enrollment	1980
Study Type	INTERVENTIONAL
Conditions	Hypertension; Hyperlipidemias
Interventions

To leverage access to patients across the primary care network, EPIC tools for identifying eligible patients, and the Way to Health platform to launch and enroll a program that will be evaluated in a clinical trial that is focused on changing patient behavior and powered to detect differences in improving blood pressure and cholesterol over 6 months for Penn Medicine patients in West/Southwest …

Active, Not Recruiting

NCT06820086 — Polygenic Risk Driven Pragmatic Statin Trial for Heart Disease Prevention


Status	Active, not recruiting
Phase	Phase 4
Sponsor	Mikk JÜRISSON
Enrollment	2714
Study Type	INTERVENTIONAL
Conditions	PRS-based Primary Prevention of CVD
Interventions

This research investigates the potential advantages of intensive preventive statin treatment for healthy men aged 45-80 and women aged 55-80 who possess a high genetic predisposition to coronary artery disease (CAD). By specifically targeting the top 20% of individuals with elevated CAD polygenic risk scores (PRS), the study seeks to find out whether this tailored approach can notably decrease …

Not Yet Recruiting

NCT07014579 — Using Heart Electrical Signals to Study How Well Treatments Prevent Dangerous Heart Rhythms in Active People


Status	Not yet recruiting
Phase	N/A
Sponsor	University of Leicester
Enrollment	40
Study Type	OBSERVATIONAL
Conditions	Inherited Cardiac Conditions; Sudden Cardiac Arrest; Ventricular Arrhythmia; Athlete; Ventricular Fibrillation

The goal of this observational study is to learn if two specific heart electrical signal patterns can help in detecting the risk of dangerous heart rhythms in athletes, and to see if exercise-based tests can be used instead of invasive hospital procedures to record this electrical signals.

The main questions it aims to answer are:

Can special ECG action potential duration markers (R2I2 and…

NCT07232069 — PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis


Status	Not yet recruiting
Phase	Phase 3
Sponsor	Duke University
Enrollment	1500
Study Type	INTERVENTIONAL
Conditions	Coronary Artery Disease Risk Factors Multiple; Coronary Artery Disease Progression; Prevention & Control; Premature Atherosclerosis
Interventions	; ;

Heart disease is the leading cause of death for men, women, and people of most racial and ethnic groups in the United States. This clinical trial will test if screening and early treatment of mild heart disease works.

PRE-EMPT will screen individuals at low 10-year risk of heart disease with heart disease risk factors to identify those who already have early cholesterol build up, also called “…

Completed Trials

NCT00315978 — The Impact of Patient Involvement in Decision-Making About Heart Disease Prevention


Status	Completed
Phase	N/A
Sponsor	University of North Carolina
Enrollment	120
Study Type	INTERVENTIONAL
Conditions	Cardiovascular Disease
Interventions

The purpose of this study is to determine whether providing patients with information about their global coronary heart disease (CHD) risk and effective risk-reducing strategies allows them to make appropriate decisions about heart disease prevention.

NCT03059472 — Strong Hearts for New York: A Rural Heart Disease Prevention Study


Status	Completed
Phase	N/A
Sponsor	Cornell University
Enrollment	182
Study Type	INTERVENTIONAL
Conditions	Heart Disease; Cardiovascular Disease; Sedentary Lifestyle; Overweight; Obesity
Interventions	;

Strong Hearts for New York is a research study which aims to reduce cardiovascular disease (CVD), improve quality of life, and reduce CVD related health care costs in rural communities. Our aim is to better understand how changes in lifestyle can affect the health of rural women and others in their communities.

Other (Unknown)

NCT01089842 — Health Coaching to Promote Physical Activity for Coronary Heart Disease Prevention


Status	Unknown
Phase	N/A
Sponsor	Corporacion Parc Tauli
Enrollment	262
Study Type	INTERVENTIONAL
Conditions	Coronary Disease; Atherosclerosis
Interventions	;

The purpose of this study is to evaluate the efficacy of motivational interviewing-based coaching to increase physical activity to achieve guidelines recommendations for cardiovascular disease prevention.

Other (Terminated)

NCT05643573 — A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke


Status	Terminated
Phase	Phase 3
Sponsor	Bayer
Enrollment	14830
Study Type	INTERVENTIONAL
Conditions	Prevention of Stroke or Systemic Embolism; Atrial Fibrillation
Interventions	; ;

Researchers are looking for a better way to treat people with atrial fibrillation (AF) and prevent stroke or systemic embolism (blood clots travelling through the blood stream to plug another vessel).

Atrial fibrillation is a condition of having irregular and often rapid heartbeat. It can lead to the formation of blood clots in the heart which can travel through the blood stream to plug anothe…