Clinical Trials for Elbow Injuries and Disorders

Source: ClinicalTrials.gov — U.S. National Library of Medicine — A database of privately and publicly funded clinical studies conducted around the world (U.S. National Library of Medicine, public domain).

This page lists clinical trials related to Elbow Injuries and Disorders from the ClinicalTrials.gov database.

Trial Summary

• Total studies: 50
• Recruiting: 14
• Active, not recruiting: 3
• Completed: 21
• Other: 12

Results are refreshed periodically and may not reflect the most current information available from ClinicalTrials.gov.

Recruiting Trials

NCT01894802 — Cortical Recording and Stimulating Array Brain-Machine Interface

The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of brain sensory cortex.

NCT05981664 — Level Up! Adaptive Gaming for Children With Upper Limb Differences

The goal of this clinical trial is to test a new one-handed video game controller adapter to determine if it helps improve how video games are played and enjoyed in children with an upper limb difference on one side. The main questions it aims to answer are:

• Is performance improved while playing video games with the adapter?
• Is user satisfaction or enjoyment improved while playing video ga…

NCT06587412 — Treatment of Lateral Epicondylalgia With Shock Waves

Lateral epicondylalgia (LET) is characterized by pain, decreased muscle strength of the wrist extensor muscles, and disability. Among the treatments proposed in the literature, both focal shockwave therapy and radial shockwave therapy have been considered effective in the management of this musculoskeletal disorder. The objective of this study is to compare the safety and effectiveness of these…

NCT07427368 — Comparison of ESWT and Ultrasound-Guided Ozone Injection in Lateral Epicondylitis

Lateral epicondylitis is a common and often debilitating condition characterized by pain over the lateral aspect of the elbow. Although many patients respond to standard conservative treatments, a subset develops a chronic and treatment-resistant form of the condition.

The primary objective of this randomized comparative clinical trial is to evaluate and compare the therapeutic effectiveness o…

NCT07178288 — Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)

This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly “turn down” pain after a cold stimulus. Participants complete brief questionnaires (basic demographics without names, a tennis-elbow symptom form, and a physical-activity form) and then have their pressure-pain threshold (PPT) test…

NCT07231471 — Platelet Rich Plasma for Musculoskeletal Conditions

The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain levels, functional abilities, and overall patient satisfaction.

This will develop a robust registry of patients treated with PRP for a range of MSK conditions. These conditi…

NCT07576829 — Wrist Heavy Slow Resistance and Shoulder Stabilization Exercises on Pain, Grip Strength and Functional Ability in Lateral Epicondylitis

The study will compare the shoulder and wrist treatment approaches to determine their effect on elbow. Thirty-two medically stable participants with active shoulder and wrist movements will be enrolled into two groups. Both groups will receive structured training for six weeks. Outcomes will be measured using standardized assessment tools. The aim is to identify the more effective strategy for …

NCT07523893 — Comparative Effects of Shockwave Therapy and Eccentric Exercises in Patients With Lateral Epicondylitis

The goal of this randomized controlled trial is to compare the effects of shockwave therapy and eccentric exercises on pain, functional ability, quality of life, grip strength and range of motion in patients with lateral epicondylitis. Participants will be randomly assigned to either Group A (Shockwave therapy) or Group B (Eccentric Exercises) using a computer-generated random number tables met…

NCT07553273 — Vibratory Anesthesia on Pain Following Corticosteroid Injections

This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics. Each individual’s perception of pain upon receiving a CSI with two out of three modes of anesthesia (control/no anesthesia, vibrational anesthesia, vapo-coolant anesthesia) will be utilized to compare these …

NCT07558564 — Evaluation of Platelet-Rich Plasma (PRP) Treatment in Tendinopathies

This multicenter, prospective, observational study, based on real-world evidence (RWE), aims to evaluate the efficacy and safety of Platelet-Rich Plasma (PRP) treatment across four types of tendinopathies: patellar, Achilles, epicondylar, and plantar fasciosis. Data collection and analysis will be conducted using the BioSmartData® platform, including hematology analyzers for PRP characterizatio…

NCT07501429 — Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury

Approximately 305,000 people live with a spinal cord injury (SCI) in the United States. Sixty percent of these individuals have tetraplegia, which can cause significant dysfunction of the arms and hands. One of the consequences of SCI is spasticity - involuntary activation of muscles that can hinder bodily functions and negatively affect participation in various aspects of life. Spasticity can …

NCT07564713 — Comparison of Extracorporeal Shock Wave Therapy and Low-Level Laser Therapy in Patients With Lateral Epicondylitis

Background:

Lateral epicondylitis is a common musculoskeletal condition characterized by pain and functional impairment of the elbow, often associated with degenerative changes in the common extensor tendon. Extracorporeal shock wave therapy (ESWT) and low-level laser therapy (LLLT) are widely used noninvasive treatment modalities; however, comparative evidence regarding their clinical and str…

NCT07634224 — Evaluation of the Effectiveness of Capacitive and Resistive Energy Transfer Therapy for Lateral Epicondylitis

This prospective, randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy of Capacitive and Resistive Energy Transfer (TECAR) therapy in patients with lateral epicondylitis. Participants will be randomly assigned to either a TECAR plus exercise group or a sham TECAR plus exercise group.

Both groups will receive a standardized home exercise program including elbow…

NCT07582510 — Telerehabilitation vs Supervised Physiotherapy for Medial Epicondylitis

This randomized controlled trial aims to compare the effectiveness of telerehabilitation and supervised physiotherapy in patients with medial epicondylitis. The primary outcome is improvement in pain and function using the Patient-Rated Elbow Evaluation (PREE). Secondary outcomes include pain intensity, grip strength, musculoskeletal ultrasound findings, adherence, and upper limb disability mea…

Active, Not Recruiting

NCT05325242 — Elbow Artery Embolization for Tennis Elbow

The purpose of this clinical research study is to examine whether embolization treatment of an elbow artery is a safe and effective way to treat elbow pain, specifically pain from tennis elbow. Embozene is a medical device made by Varian marketed in the United States for the treatment of hypervascular tumors and arteriovenous malformations. It consists of thousands of microscopic spheres that a…

NCT07461311 — Manual Therapy on Lateral Elbow Pain

This randomised, controlled, double-blind experimental study is designed to evaluate the efficacy of a standardised manual physiotherapy protocol for treating lateral epicondylalgia of the humerus, commonly known as ’tennis elbow’. The study will compare the results for patients receiving active treatment with those for a control group who will follow a watchful waiting approach. Secondary obje…

NCT07406802 — Association Between Racket Stiffness and Lateral Epicondylalgia in Tennis Players

Background. Lateral epicondylalgia is common in tennis and is associated with pain and functional limitation. Although racket stiffness has been experimentally linked to vibration transmission, its clinical association with this condition in tennis players remains insufficiently studied.

Objective. To evaluate the association between racket stiffness and the presence of lateral epicondylalgia …

Not Yet Recruiting

NCT07444996 — Effect of Magnetotherapy Combined With Cold Application and Exercise in Patients With Lateral Epicondylitis

This study aims to evaluate the effectiveness of magnetotherapy in the treatment of lateral epicondylitis (tennis elbow). Lateral epicondylitis is a common musculoskeletal condition characterized by pain and tenderness over the outer part of the elbow, often associated with repetitive wrist extension and gripping activities. It may cause reduced grip strength, functional limitations, and decrea…

NCT07484516 — Effects of Eccentric Exercises Along With Muscle Energy Technique in Lateral Epicondylitis

This study is intended to find the effects of Eccentric exercises along with muscle energy technique (MET) on pain, functional disability, range of motion and grip strength in Lateral Epicondylitis. For this trial, participants will be enrolled with their consent after assessing on basis of inclusion & exclusion criteria from orthopedic workshop, Jinnah post graduate medical center Karachi. To…

NCT07495254 — Effectiveness of Combined Super Inductive System (SIS) Therapy With Therapeutic Exercise and Health Education in Lateral Elbow Tendinopathy

Background Lateral epicondylalgia is the most common cause of lateral elbow pain and affects approximately 1% to 3% of the population. It reduces strength, functionality, and quality of life, leading to limitations in work and daily activities and representing a relevant public health concern.

Current scientific evidence suggests conservative physical therapy as the first-line treatment; howev…

NCT07544914 — Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain

This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer’s elbow or carpal tunnel syndrome. Approximately 40 participants will be randomly assigned to active or sham stimulation delivered over two consecutive days. Outcomes, including pressure pain threshold, sub…

NCT07550322 — Dry Needling vs ESWT in Lateral Epicondylitis

This randomized single-blind controlled trial aims to compare the effectiveness of ultrasound-guided dry needling and extracorporeal shock wave therapy in patients with lateral epicondylitis. Sixty participants aged 18-65 years will be randomized into two groups. The dry needling group will receive ultrasound-guided tendon fenestration once weekly for five sessions, while the ESWT group will re…

NCT07589725 — Mulligan Mobilization in Lateral Elbow Tendinopathy

The aim of this study is to investigate the short-, medium-, and long-term effects of Mulligan Mobilization with Movement (MWM) added to an exercise program on pain, functionality, and biomechanical parameters in individuals with lateral elbow tendinopathy, compared to sham mobilization and exercise-only interventions.

The primary hypothesis is that the addition of true MWM to exercise will re…

NCT07259382 — Neuro-Inflammation in Extremity Trauma: Risk Verification in Elbow Trauma: The NERVE Study

The primary goal of this proposal is to improve the understanding of the mechanisms causing persistent pain and disability in elbow fracture patients and their associated functional limitations. The specific objectives are as follows for elbow fractures:

1) To describe NI mechanisms using biomarkers; 2) To identify factors related to increased NI biomarkers level; 3) To describe the associati…

NCT07648849 — Arthroscopic Versus Open Management of Lateral Epicondylitis Elbow (Randomized Control Trial)

Arthroscopic Versus Open management of lateral epicondylitis elbow (Randomized Control Trial)

Completed Trials

NCT00437762 — Effectiveness of Botulinum Toxin Injection in the Tennis Elbow Treatment

Some studies valued the effectiveness of botulinum toxin. Results are contradictory and we need more studies. The purpose of the study is to compare the effectiveness of botulinum toxin injection with placebo in the treatment of tennis elbow unrelieved by usual medical care performed during 6 months. Method : It is a double blind randomized controlled trial. Principal criteria of assessment is …

NCT03487250 — Percutaneous US Guided Elbow Tenotomy With the TenJet HydroSurgery System

To evaluate the acute and long-term clinical outcomes of tenotomy with the TenJet System in patients with elbow tendinosis.

NCT03978897 — Trial of Blood Flow Restriction Plus Physical Therapy vs. Physical Therapy Alone for Lateral Epicondylitis

Open label randomized controlled trial comparing evidenced based physical/occupational therapy vs. physical/occupational therapy including blood flow restriction tourniquet in the treatment of lateral epicondylitis (tennis elbow).

NCT04686799 — Doxycycline for Elbow Tendinopathy

To evaluate the feasibility of subantimicrobial -dose (SD) doxycycline to improve outcomes of nonsurgical management of elbow tendinopathy via matrix metalloproteinase (MMP) inhibition as well as evaluate if participants will be compliant to with prescribed medication and exercise treatment. Our working hypothesis is that patients with elbow tendinopathy will be receptive to treatment with SD-d…

NCT07627932 — Comparison of the Effectiveness of Blood Flow Restriction Exercise and Eccentric Exercise in Lateral Epicondylitis

This study compared three different treatment approaches for lateral epicondylitis (tennis elbow), a common condition that causes pain on the outside of the elbow.Twenty-seven patients diagnosed with lateral epicondylitis were randomly assigned to one of three treatment groups for 6 weeks:Group 1 - Blood Flow Restriction Exercise (BFRE): Patients performed wrist strengthening exercises using li…

NCT07661615 — Arthroscopic or Open Evaluation of Posterolateral Instability Associated With Lateral Epicondylitis

The elbow is a complex joint made up of three bones, three joints, and three ligaments. Repeated microtraumas can lead to ligament injuries and instability, tendon damage, or degenerative processes affecting the bones, cartilage, and bursae. As a result, elbow pain is not uncommon, and diagnosing the underlying problem is not always easy. One reason for this is the complex anatomy packed into a…

NCT07420764 — Comparison Of The Effectiveness Of Wrist Splint And Kinesiotaping Treatments In Patients With Lateral Epicondylitis

Lateral epicondylitis, also known as tennis elbow, is a common condition that causes pain in the elbow and forearm, especially in people who perform repetitive wrist movements. In most patients, symptoms improve over time, but in some cases, pain may persist for longer periods.Exercise programs are commonly used in treatment to reduce pain and improve arm function. Kinesiology taping is another…

NCT07620678 — Comparison of ESWT and Single-Session 5% Dextrose Prolotherapy in Lateral Epicondylitis

Lateral epicondylitis is a common musculoskeletal disorder associated with pain and impaired upper extremity function. The aim of this study was to compare the effectiveness of extracorporeal shock wave therapy (ESWT) and single-session 5% dextrose prolotherapy (DPT) in patients with lateral epicondylitis and to evaluate the relative superiority of these treatment approaches during short- and m…

NCT07638488 — Trigger Point Extracorporeal Shock Wave Therapy in Patients With Lateral Epicondylitis

This randomized controlled study evaluates the effect of extracorporeal shock wave therapy applied to the extensor carpi radialis brevis trigger point in patients with lateral epicondylitis. Participants receive active extracorporeal shock wave therapy to the lateral epicondyle region. In addition, one group receives active extracorporeal shock wave therapy to the extensor carpi radialis brevis…

NCT07643740 — COMPARATIVE EFFECTS OF DRY NEEDLING AND NEURAL MOBILIZATION ON PAIN, STRENGTH AND RANGE OF MOTION IN PATIENTS WITH GOLFER’S ELBOW

This randomized clinical trial aims to compare the effectiveness of Dry Needling and Neural Mobilization in patients diagnosed with Golfer’s Elbow (Medial Epicondylitis). The study will evaluate the effects of both interventions on pain intensity, grip strength, and range of motion. Participants will be randomly allocated to either the Dry Needling group or the Neural Mobilization group and tre…

NCT07351942 — Effectiveness of Low-Load Resistance Training With Blood Flow Restriction in Lateral Epicondylitis

Lateral epicondylitis, commonly known as tennis elbow, is a frequent musculoskeletal condition that causes pain, reduced grip strength, and functional limitations in daily activities. Exercise-based rehabilitation is a key component of treatment; however, the optimal exercise approach remains uncertain. Low-load resistance training combined with blood flow restriction (LLRT-BFR) has emerged as …

NCT07146620 — Effectiveness of Radial Nerve Mobilization for Chronic Epicondylalgia

Effectiveness of radial nerve mobilization techniques and their interfaces for treating chronic epicondylalgia

Intervention: This is a randomized controlled clinical trial that will evaluate the effectiveness of adding radial nerve and its interface mobilization techniques to conventional musculoskeletal treatment.

Participants: Patients over 18 years of age with a diagnosis of chronic epicon…

NCT07277127 — Effect of Percutaneous Electrolysis Combined With Exercise on Pain and Function in Chronic Lateral Epicondylitis

The aim of this randomized controlled trial is to compare the effects of percutaneous electrolysis combined with exercise versus exercise alone on pain and function in patients with chronic lateral epicondylitis. Participants will be randomly allocated into two parallel groups. The control group will receive a 2-week exercise program including stretching and eccentric strengthening exercises fo…

NCT07187102 — Ultrasonographic Response to Cervical and Upper Thoracic SNAG in Medial Epicondylitis

Aim of the work :

1. To detect if there is any change would occur in the neovascularity and echogenicity after using cervical and upper thoracic SNAG or not in ME patients.
2. To find the effect of cervical and upper thoracic SNAG on pain, function of upper extremities, grip strength in ME comparing with traditional treatment alone

NCT07236554 — Blood Flow Restriction Training Versus Mulligan Technique in Treatment of Lateral Epicondylitis

The purpose of this study is to evaluate the effectiveness of blood flow restriction training (BFRT) verses Mulligan’s technique in improving pain, grip strength, and functional outcomes in patients with lateral epicondylitis (LE).

NCT07604454 — Muscle Energy Technique Combined With Mulligan Technique in Tennis Elbow

This randomized controlled trial aims to evaluate the effectiveness of Muscle Energy Technique (MET) combined with Mulligan Mobilization With Movement (MWM) in patients with lateral epicondylitis (tennis elbow). The study compares the combined intervention with Mulligan technique and routine physical therapy alone. Outcomes including pain intensity, functional disability, and quality of life wi…

NCT07127302 — Correlation of Ultrasonographic Findings With Clinical Parameters in Patients With Lateral Epicondylitis

Evaluation and Clinical Correlation of Tendons Using Power Doppler, SWE, Microvascular Flow (MV-Flow) Imaging and B-Mode Ultrasonography in Patients with Lateral Epicondylitis.

NCT07576140 — Effects of Mobilization With Movement and Active Release Technique in Patients With Lateral Epicondylitis

This study is a randomized controlled trial (RCT) investigating the effectiveness of Mobilization with Movement (MWM) combined with Active Release Technique (ART) in the management of lateral epicondylitis. A total of 44 participants, aged 18-55 years with a clinical diagnosis of lateral epicondylitis (duration ≥6 weeks), will be randomly assigned into two groups. The intervention group will re…

NCT07475663 — Counterpain PXM Versus Diclofenac Versus Piroxicam

The goal of this clinical trial is to learn if a gel containing Piroxicam plus Counterirritant (warming/cooling ingredients) is as effective and safe as two other common anti-inflammatory gels for treating acute muscle, bone, and joint pain in adults aged 18-60. The main questions it aims to answer are:

Does the Piroxicam plus Counterirritant gel provide a similar level of pain relief as the s…

NCT07667491 — Effects of 8 Weeks of Two Exercise Programs on Risk Factors Associated With Epicondylitis in Amateur Padel Players

Background: The physical demands of padel can increase the risk of injuries, particularly lateral epicondylitis in the elbow. Key risk factors include deficits in forearm muscle strength and rotator cuff weakness. Prevention programs focus on forearm strengthening, with no studies on rotator cuff strength. This study aims to compare two exercise programs designed to reduce risk factors for late…

NCT07424794 — Mobilization With Movement Verses Cyriax Techniques Among Athletes With Lateral Epicondylitis

This randomized controlled trial aims to compare the effectiveness of Mobilization with Movement (MWM) and Cyriax techniques in athletes diagnosed with lateral epicondylitis (tennis elbow). Lateral epicondylitis commonly causes pain, reduced grip strength, and impaired proprioception, particularly in racquet and throwing sports players. A total of 56 participants aged 25-40 years with symptoms …

Other (Terminated)

NCT00426985 — Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis

The purpose of this study is to evaluate the effect of a ketoprofen topical patch on the pain associated with tendonitis or bursitis of the shoulder, elbow or knee

Other (Suspended)

NCT05237869 — Blood Flow Restriction & Tennis Elbow Rehab

Lateral epicondylitis (LE), often referred to as “tennis elbow” is a common and debilitating overuse injury affecting 1-3% of adults annually. LE is most often defined as a syndrome of pain near the area of the lateral epicondyle of the elbow commonly effecting the origin of the extensor carpi radialis brevis with associated weakness; it most commonly effects the dominant arm. The best treatmen…

NCT06846593 — The Comparison of Semiconductor Embedded Therapeutic Arm Sleeves for the Treatment of ECRB Tendinopathy

This study seeks to identify patient reported and clinically measured outcomes for pain management and elbow function with application of semiconductor embedded fabric combined with PRP+ASC injections in the affected area.

NCT07027059 — Neural Mobilization Exercises on Pain and Central Sensitization

This study aims to investigate the effects of neural mobilization exercises on central sensitization and pain characteristics in individuals with lateral epicondylitis. Enrolled participants will be randomly assigned to two groups. One group will receive routine exercises and ESWT treatment, while the other group will receive neural mobilization exercises in addition to routine exercises and ES…